Hashimoto's thyroiditis is the most frequent autoimmune disease with genetic and environmental aetiologies. Viral infections have been postulated as one of the factors that may trigger autoimmune diseases. Many studies suggest that Herpes simplex virus infections are involved in a variety of autoimmune diseases. We report the case of three patients presenting for the first time herpes labialis ...

Herpes labialis are the most frequent clinical manifestations of HSV-1 infection.Epithelial cells are able to respond to HSV-1 presence inducing the expression of IL-6,IL-1, TNF-α and IL-8. These proinflammatory cytokines have a function in the acute-phase response mediation, chemotaxis, inflammatory cell activation and antigen-presenting cells. In the human epithelial cell ...

Early treatment of recrudescent herpes labialis over the symptomatic area has been claimed to inhibit the clinical signs of recrudescent herpes labialis. Electronic infrared thermography can both recognise the prodromal phase and identify the area requiring drug therapy. Our objective was to use infrared thermography to identify prodromal herpes and follow the response to topical acyclovir crea...

Purpose: The aim of this study is to compare the effects acyclovir and penciclovir creams in treatment recurrent herpes labialis. 
 Materials Methods: Seventy patients with pre-diagnosed labialis lesions were enrolled study. Diagnosis was confirmed HSV-1 IgM antibody test. Patients separated under 2 groups as cream. Both agents applied until complete healing seen. Burning, itching bleeding...

Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed...

Lymphocyte responses to herpes simplex virus (HSV) were studied in 23 patients with recurrent herpes labialis and in 19 control subjects. Lymphocytes of seropositive, but not seronegative, controls responded to HSV by thymidine incorporation, and the supernatant fluids inhibited the migration of guinea pig macrophages. Lymphocytes from patients with a recurrent herpetic lesion responded to HSV ...