Pregnancy is associated with increased sweet food cravings, but the relationship between sweet cravings and dietary intake remains uncertain. Gestational diabetes mellitus (GDM) is glucose intolerance first recognized during pregnancy. GDM may further perpetuate sweet food cravings and intake in pregnancy, although this has not been investigated. This study longitudinally assessed sweet food cr...

The sweet taste receptors present in the taste buds are heterodimers comprised of T1R2 and T1R3. This receptor is also expressed in pancreatic β-cells. When the expression of receptor subunits is determined in β-cells by quantitative reverse transcription polymerase chain reaction, the mRNA expression level of T1R2 is extremely low compared to that of T1R3. In fact, the expression of T1R2 is un...

The study was carried out in order to find out the effect of substitution of wheat flour with sweet potato flour of two local varieties (Local Sada and Local Lal) on the quality of bread. This study was also concerned with the analysis of proximate compositions of sweet potato and results showed that, fresh local sada and local lal sweet potato varieties contained moisture 70.10 and 66.78%; ash...

OBJECTIVES The aim of the study was to evaluate the influence of sweet taste perception on dietary habits in Saudi schoolchildren. In addition, the relationship between dietary habits and both caries and BMI was studied. METHODS A cross-sectional observational study comprising 225 schoolchildren aged 13-15 years from Jeddah, Saudi Arabia, was conducted. The consumption frequency of certain fo...

The preference of sweet taste in rats is a phenomenon that is influenced by many factors. Drugs, sex, and age are three important aspects to consider when determining the underlying mechanisms that influence increased intake in the presence of sweet taste. Research has shown that drugs acting on receptors and neurotransmitters of brain mechanisms relevant to hedonic and reinforcement effects ca...

BACKGROUND Glial dysfunction has been purported to be important to the pathophysiology of bipolar illness. However, manic behavior has not been previously demonstrated to result as a consequence of glial pathology. The aim of the current study was to assess the behaviors of the glial-specific sodium pump alpha2 subunit (ATP1A2) knockout (KO) heterozygote mice to determine if a glial-specific ab...

Humans love the taste of sugar and the word "sweet" is used to describe not only this basic taste quality but also something that is desirable or pleasurable, e.g., la dolce vita. Although sugar or sweetened foods are generally among the most preferred choices, not everyone likes sugar, especially at high concentrations. The focus of my group's research is to understand why some people have a s...