CD8+ T cells are thought to play an important role in protective immunity to tuberculosis. The major histocompatibility complex class I subtype HLA-A*0201 is one of the most prevalent class I alleles, with a frequency of over 30% in most populations. HLA-A*0201 transgenic, H-2Db/mouse beta2-microglobulin double-knockout mice (HHD) which express human HLA-A*0201 but no mouse class I, was shown t...

BACKGROUND Resurgence of interest in home haemodialysis (HHD) is, in part, due to emerging evidence of the benefits of extended HD regimens, which are most feasibly provided in the home setting. Although specific HHD therapy established at home such as nocturnal HD (NHD) has been reported from individual programmes, little is known about overall HHD success. METHODS The study included 166 pat...

Mobile Augmented Reality (AR) applications are typically deployed either on head mounted displays (HMD) or handheld displays (HHD). This paper explores novel interaction techniques for a combined HHD-HMD hybrid system that builds on the strengths of each type of device. We use the HMD for viewing AR content and a touch screen HHD for interacting with the content. A prototype system was develope...

CONTEXT Hand-held dynamometry (HHD) has been shown to be a reliable, objective way to obtain strength measurements in elderly and physically impaired subjects. OBJECTIVE To estimate the intratester, intertester, and intersession reliability of HHD testing of lower extremity movements in young, healthy subjects. DESIGN Repeated measures. SETTING Sports medicine laboratory. PARTICIPANTS N...

In this paper, we consider the recognition problem on a class of perfectly orderable graphs, namely, the HHD-free graphs; such graphs do not contain any induced subgraph isomorphic to a house, a hole, or a domino. We prove properties of the HHD-free graphs which enable us to present an O(n m)-time and O(n + m)-space algorithm for determining whether a graph on n vertices and m edges is HHD-free...

Specific immunotherapy of prostate cancer may be an alternative or be complementary to other approaches for treatment of recurrent or metastasized disease. This study aims at identifying and characterizing prostate cancer– associated peptides capable of eliciting specific CTL responses in vivo . Evaluation of peptide-induced CTL activity in vitro was done following immunization of HLA-A2 transg...

BACKGROUND Hailey-Hailey disease (HHD) is a rare autosomal dominant skin condition. The ATP2C1 gene was identified as the defective gene in HHD. To date, 166 pathogenic mutations in ATP2C1 have been observed worldwide. The aim of this study was to identify variations in HHD and summarize the features of the mutations identified in China. MATERIAL AND METHODS We examined 2 familial and 2 sporadi...

Hailey-Hailey disease (HHD) is an autosomal dominant disorder in which the ATP2C1 gene has been implicated. Many mutations of this gene have been detected in HHD patients. To analyze such mutations in HHD and summarize all those identified in Chinese patients with this disease, we examined four familial and two sporadic cases and searched for case reports and papers by using the Chinese Biologi...

Abstract Background and Aims Despite being energy resource-intensive, hemodialysis (HD) is the most common therapy for end stage kidney disease. Considering extensive amount of energy, water, consumables involved, this modality expected to have a significant environmental impact. Through comparative lifecycle assessment (LCA), study aims analyze impacts in British Columbia, Canada. Method A pro...

Background: Hypertensive heart disease (HHD) is the constellation of abnormalities characterized by cardiac complications. Despite advancements in management of hypertension and access to medical care, incidence of HHD is an alarmingly increasing through time. However, information on determinants of HHD studies is limited in Ethiopia. We assessed determinants of HHD among adult hypertensive pat...