Transrectal High Intensity Focused Ultrasound treatment is currently being studied as a minimally invasive therapy of localized prostatic cancer. In is a novel therapeutic procedure in which a highly focused transducer induces tissue coagulation necrosis by sharp temperature increase inside the prostatic tissue. Generally accepted belief holds that the tissue necrosis is caused by two principal...

OBJECTIVE To evaluate the feasibility of using computer-assisted, deformable image registration software to enable three-dimensional (3D), multi-parametric (mp) magnetic resonance imaging (MRI)-derived information on tumour location and extent, to inform the planning and conduct of focal high-intensity focused ultrasound (HIFU) therapy. PATIENTS AND METHODS A nested pilot study of 26 consecut...

Background/introduction Breast fibroadenomata (FAD) are the most common breast lesions in woman. For palpable lesions, three options are available: reassurance (with or without follow-up), vacuum assisted mammotome (VAM) or surgical excision. High intensity focused ultrasound (HIFU) is a non-invasive ablative technique in which an ultrasound (US) beam propagates through tissue as a high-frequen...

Liver ablation is challenging in high-intensity focused ultrasound (HIFU) because of the presence of ribs and great inhomogeneity in multi-layer tissue. In this study, angular spectrum approach (ASA) has been used in the wave propagation from phased-array HIFU transducer, and diffraction, attenuation and the nonlinearity are accounted for by means of second order operator splitting method. Bioh...

A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impra...

BACKGROUND High-intensity focused ultrasound (HIFU) is considered to be an alternative to surgery. Extracorporeal ultrasound-guided HIFU (USgFU) has been clinically used to treat solid tumors. Preliminary trials in a small sample of a Western population suggested that this modality was safe. Most trials are performed in China thereby providing comprehensive data for understanding the safety pro...

INTRODUCTION Therapy of choice for symptomatic vascular malformations consists of surgery, sclerotherapy, or embolization. However, these techniques are invasive with possible complications and require hospitalization. We present a novel non-invasive technique, i.e., magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablation, for the treatment of a vascular malformation in a...

High intensity focused ultrasound (HIFU) is a method for non-invasive tumor therapy. The high energy density in the focal spot leads to local tissue heating and finally to thermal coagulation in the focal area (Fig.1) [1]. To monitor this treatment, the focus position can be detected online with temperature sensitive MR imaging. However characterization of the induced lesion is difficult. It ha...

OBJECTIVE The aim of this study was to evaluate the efficacy, safety and sexual life quality outcomes of ultrasound-guided high-intensity focused ultrasound (HIFU) ablations for the treatment of patients with symptomatic adenomyosis and uterine volumes >200 cm(3). METHODS In our prospective clinical trial 47 patients with uterine volumes >200 cm(3) and symptomatic adenomyosis were treated wit...