Brain region coordination in learning Gamma-frequency oscillations have been hypothesized as a physiological mechanism of interregional communication the brain. However, until now, all supporting data correlational and thus indirect. Fernández-Ruiz et al. examined gamma-frequency activity spike coupling between entorhinal cortex hippocampal dentate gyrus during after selective perturbation timi...

Objective The hippocampal circuit integrity is crucial for learning and memory. Despite the existing reports on hippocampal–dependent memory impairment due to noise stress, there are only a few studies on the effect of noise stress on anatomical structure of hippocampus. The present study is aimed to investigate the likely effects of chronic noise exposure on the volume of rat hippocampus. Mate...

Purpose: The aim of this study is to comparatively examine the possibility reducing exposure dose organs at risk, such as hippocampus and lens, improving distribution planned target volume with without use a head-tilting base plate in hippocampal-sparing whole-brain radiotherapy using tomotherapy. Methods: Five paired images head computed tomography tilt were analyzed. planning contoured accord...

hippocampal neural stem/progenitor cells (hipp-ns/pcs) of the adult mammalian brain are important sources of neuronal and gial cell production. in this study, the main goal is to investigate the plasticity of these cells in neuronal/astroglial differentiations. to this end, the differentiation of the hipp-ns/pcs isolated from 3-month-old wistar rats was investigated in response to the embryonic...

The anterior thalamic nuclei are a vital node within hippocampal-diencephalic-cingulate circuits that support spatial learning and memory. Reflecting this interconnectivity, the overwhelming focus of research into cognitive functions has been processing. However, there is increasing evidence extend beyond realm. This work highlighted how these required for certain classes temporal discriminatio...

Anredera cordifolia extract increased learning and memory by enhancing levels of hippocampal BDNF, PSD95, NR2A, p-CREB in SAMP8 mice.

Objective: The present study investigates the effect of Tiliacora triandra leaf extract on spatial learning, memory, and learning flexibility as well as hippocampal choline acetyltransferase (ChAT) activity in mice.  Materials and Methods: Thirty male ICR mice were randomly divided into three groups including 10% Tween 80, T. triandra 300 mg/kg and T. triandra 600 mg/kg. All administrations wer...

Introduction: Research has shown that gold nanoparticles (AuNPs) can damage the physiological processes of brain tissue. Given the antioxidant properties of gingerol (GING), this study aimed to determine the protective effect of 6-gingerol on hippocampal levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), DNA oxidative damage, and the amount of Bax and Bcl2 apoptosis ...

introduction: many studies have shown that amygdala kindling produces synaptic potentiation by induction of changes in the neuronal electrophysiological properties and inward currents both in epileptic focus and in the areas which are in connection with the epileptic focus and have important role in seizure development and progression such as hippocampal ca1 region. however, cellular mechanisms...

objective(s):the present study investigated the effect of long-term mild cerebral hypoperfusion induced by permanent unilateral (right) common carotid artery occlusion (uco) on the dorsal hippocampal neurons in rats. materials and methods:sixty four male sprague-dawley rats aged 4 months were divided into two groups of sham and uco. these two groups were further divided into 4 sets of histopath...