objective(s): some histopathological alterations take place in the ischemic regions following brain ischemia. recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia. here, we investigated the probable neuroprotective effects of crocin on the brain infarction and histopathological changes after transient model of focal cerebral...

background: besides of transmitting several diseases to animals, and tick paralysis, ornithodoros lahorensis induce skin lesions. this experiment was done to determine histopathological features of adult o. lahorensis bite on rat. methods: in this investigation adult male rats were infested with o. lahorensis ticks. animals were divided into two groups and euthanized two days and two weeks afte...

Background: Fibroblastic focus (FF) is the typical histopathological feature of idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP). A study was undertaken to analyse FF at diagnosis, to analyse the histopathological findings at necropsy, and to examine their association with the course of the disease. Methods: A retrospective study was made of 76 UIP cases collected over a p...

BACKGROUND Fibroblastic focus (FF) is the typical histopathological feature of idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia (UIP). A study was undertaken to analyse FF at diagnosis, to analyse the histopathological findings at necropsy, and to examine their association with the course of the disease. METHODS A retrospective study was made of 76 UIP cases collected over a p...

BACKGROUND Sirtuin1 (Sirt1) is a member of highly conserved proteins and has been implicated as a tumor promoter as well as a tumor suppressor. One of the mechanisms involves deacetylation of retinoblastoma protein, thereby inhibiting the tumor suppressor function. No study has been reported on the expression of Sirt1 in retinoblastoma. METHODS We assessed the expression of Sirt1 in sections ...

Inflammatory bowel diseases (IBDs) are chronic inflammatory that often relapse and divided into two types, Crohn’s disease (CD) ulcerative colitis (UC). Histopathological findings in colonic mucosal biopsy with clinical diagnosis suspicious IBD can vary overlap. Therefore, criteria guidelines have been created to improve the diagnostic accuracy. This descriptive observational study was performe...

This study aimed to investigate the histopathological feature of sacroiliitis and to examine its relationship with imaging features using various imaging techniques. Computed-tomography (CT)-guided needle biopsy of the sacroiliac (SI) joints was performed in 36 patients with spondyloarthritis. Histopathological examination was performed on the samples and subjects were divided as with or withou...

-Three hundred and nineteen patients with primary adenocarcinoma of the ovary were studied to define those factors, many of them histopathological, which influence survival. The paper considers the stage of spread at the time of operation, the histological type of the tumour, its grade and in particular its mitotic activity, which proved a significant feature per se in assessing prognosis in ov...

We propose a fast and accurate method for counting the mitotic figures from histopathological slides using regenerative random forest. Our method performs automatic feature selection in an integrated manner with classification. The proposed random forest assigns a weight to each feature (dimension) of the feature vector in a novel manner based on the importance of the feature (dimension). The f...