background: polycystic ovarian syndrome (pcos) represent one of the common endocrine disorders which influence around 8% of reproductive women whom usually suffering from obesity and increase cardiovascular risk. serum homocysteine levels are associated with bad impact on endothelial functions and considered as an independent risk factor for cardiovascular disease. objective: the aim was to stu...

Homocysteine thiolactone is a highly reactive homocysteine derivative that can react easily with proteins. Protein homocysteinylation has been suggested as a possible mechanism underlying the pathological consequences of impaired homocysteine metabolism. Homocysteine inhibits key steps of angiogenesis and tumor invasion. It can be hypothesized that homocysteine thiolactone could mimic the descr...

Homocysteine is an independent cardiovascular disease (CVD) risk factor modifiable by nutrition and possibly exercise. While individuals participating in regular physical activity can modify CVD risk factors, such as total blood cholesterol levels, the impact physical activity has on blood homocysteine concentrations is unclear. This review examines the influence of nutrition and exercise on bl...

objective: level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. we assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. materials and methods: a cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. all subjects had type 2 diabetes. data in...

background and objectives: type 2 diabetes is the most prevalent form of diabetes mellitus and is associated with a variety of complications. homocysteine is an important independent risk factor for atherosclerotic diseases in both diabetic and non diabetic subjects. the association between these two is still unclear. the aim of this study was to assess the serum homocysteine levels in uncompli...

Introduction: Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membrane. Antiphospholipid antibodies are a group of autoantibodies found in patients with autoimmune diseases. Due to the risk for thrombotic events in autoimmune diseases, we decided to evaluate the correlation between pemphigus vulgaris and predictive elements of atherothrombosis including antiphospho...

Does Physical Activity Level Affect Homocysteine and Obesity Variables in Women with Cardiovascular Disease?

Decrease in the activity of methylenetetrahydrofolate reductase (MTHFR) increases level homocysteine. MTHFR C677T gene polymorphism has been reported as a well-known cause elevated homocysteine associated with cerebral venous sinus thrombosis (CVST). A 34-year-old male was admitted severe headache after generalized seizure. Brain magnetic resonance venography showed thrombus superior sagittal s...

Background: Alzheimer's disease is the most common form of dementia in the elderly. Serum levels of homocysteine have been related to increased cortical and hippocampal atrophy. We aimed to determine the serum levels of homocysteine, folate, and vitamin B12 in patients with Alzheimer's disease. Methods: Blood levels of homocysteine and its biological determinants, folate, and vitamin B12 were m...

Objective: Vitamin B12 deficiency is a common health issue in children. Though the sensivity of serum vitamin measurement for diagnosis low, combined methylmalonic acid, homocysteine and holotranscobalamin have been reported to be more specific biomarkers early accurate diagnosis. In this study, we aimed verify children by measuring homocysteine, determine accuracy them.
 
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