A three year old hyperactive female child presented with a midline neck swelling of one year duration. Clinical examination revealed a nodule in the isthmus of thyroid. Her Thyroid Stimulating Hormone (TSH) was suppressed and Free T3 and Free T4 levels were elevated. Radionuclide scintigraphy showed a hyperfunctioning nodule in the isthmus of thyroid. Patient was administered antithyroid medica...

Introduction: Various radiopharmaceuticals, including 67Ga, 201Tl, and 99mTc-sestamibi have been used to differentiate benign from malignant thyroid nodules. 99mTc-Tetrofosmin, a lipophilic cationic radiotracer, and 99mTc-sestamibi have also been reported to accumulate in thyroid tumors. In this study, we evaluated the role of 99mTc-Tetrofosmin in the differentiation of malignant from ben...

Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of thyroid gland fails to develop. It is much rarer in males. There is a higher incidence of associated thyroid disorders in patients with thyroid hemiagenesis; therefore early and prompt diagnosis is important for children. We present the ultrasonographic and scintigraphic findings of thyroid hemiagenesis in an eight-year-old-...

We describe a 39-year-old woman presenting with a painless solitary thyroid nodule, initially without signs suggesting thyroiditis. The serum level of thyrotropin was suppressed whereas those of thyroxine and triiodothyronine were normal. Fine needle aspiration cytology showed no signs of inflammation or malignancy. One week later, the patient felt pain and tenderness on her neck, and erythrocy...

Accepted 23 April 1998 Summary We describe a 39-year-old woman presenting with a painless solitary thyroid nodule, initially without signs suggesting thyroiditis. The serum level ofthyrotropin was suppressed whereas those of thyroxine and triiodothyronine were normal. Fine needle aspiration cytology showed no signs ofinflammation or malignancy. One week later, the patient felt pain and tenderne...

A 68-year-old man had a rapidly growing, painless neck mass, thought to be nodular goiter. Ultrasonography showed a giant, heterogeneous mass occupying the middle and superior poles and protruding outside of the left thyroid lobe. The results of the thyroid function tests were normal. Thyroid scintigraphy revealed a large hypoactive nodule in the left thyroid lobe. Complete surgical removal of ...

Hyperfunctioning nodules of the thyroid are thought to only rarely harbor thyroid cancer, and thus are infrequently biopsied. Here, we present the case of a patient with a hyperfunctioning thyroid nodule harboring thyroid carcinoma and, using MEDLINE literature searches, set out to determine the prevalence of and characteristics of malignant "hot" nodules as a group. Historical, biochemical and...

The evaluation and management of thyroid nodules remains an area of controversy. The past decade has witnessed two important advances. The increased availability and acceptance of fine-needle aspiration biopsy of thyroid nodules has dramatically altered the clinician's approach to this disease, and provides for the single most precise method for selecting appropriate patients for surgery. The i...

Thyroid carcinoma is not uncommon in patients with hyperthyroidism. However, the risk of malignancy in patients with autonomously functioning nodules continues to be underestimated in clinical practice, possibly due to the belief of rare co-existence of a "hot" nodule and thyroid carcinoma. We present hereby a man with hyperthyroidism due to a thyroid toxic adenoma, who was subjected to surgery...