epidermal growth factor (egf), a growth factor involved in cell growth and differentiation, is a small polypeptide with molecular weight of approximately 6 kda known to be present in a number of different mammalian species. experimental studies in animals and humans have demonstrated that the topical application of egf accelerates the rate of epidermal regeneration of partial-thickness wounds a...

conclusions the her3 expression in developmental odontogenic cysts was higher than that in inflammatory odontogenic cysts. the higher rate of her3 expression in okc may justify inherent growth potential, stimulation-independent proliferation capability, invasive growth and high recurrence rate of the cyst accepted today as a tumor. results the her3 expression had positive results in 52.4% of ok...

High levels of expression of either the epidermal growth factor receptor or the receptor-like HER2/neu gene product p185HER2 have been observed in a variety of human malignancies. Because of the association of this high level expression with certain human tumors, we have generated a panel of monoclonal antibodies specific for either the epidermal growth factor receptor or p185HER2 to study thei...

results a low adc value was associated with lymph node metastasis (p < 0.01) and with high ki-67 protein levels (p = 0.03). there were no significant differences in the adc values among the histological grade (p = 0.48), molecular subtype (p = 0.51), tumor size (p = 0.46), and p53 protein level (p = 0.62). conclusion the pre-operative use of the 3.0 tesla dwi could provide information about the...

Positive regulation of epidermal growth factor receptor signalling is related to many human malignancies. Besides overexpression and gain of function mutations, the escape from negative regulation through an increase in epidermal growth factor receptor stability has evolved as yet another key factor contributing to enhanced receptor activity. Intensive research over the past years has provided ...

Tumor-related vessel length (TVE) was quantified as the number of pixels skeletonized tumor vessels on ultrafast dynamic contrast-enhanced MRI (UF-DCE MRI). The association between TVE and breast cancer subtypes investigated. Invasive presenting with human epidermal growth factor receptor 2 (HER2) associated increased tumor-related length.