We investigated the in vitro transfer of three parathyroid hormone (PTH) fragments (amino acids 35-84, 44-68 and 65-84) through human placenta at term. The perfused and transferred fragments were measured radioimmunologically and identified by three different methods: high-pressure-liquid chromatography (HPLC), preparative flat-bed electrofocusing (PEGG), and gel filtration (GF). The study demo...

The placenta of mammals is a very adaptable organ that accomplishes many critical functions necessary for the well-being of the host and developing fetus. For example, the placenta serves as an attachment site to secure the developing fetus to the uterus, and it transports nutrients from the maternal to the fetal compartment. During the evolution of viviparity, the placenta has assumed various ...

background and aim: horseshoe placenta is a variant of ring-shaped placenta. ring-shaped placenta is a rare anomaly seen in fewer than 1 in 6000 deliveries, which could be seen as horseshoe shape due to atrophy in a portion of the ring. this report refers to a possible relationship between the horseshoe shape placenta and preterm labor; although it has not been yet validated in the literature. ...

Placenta is a unique organ, without which the very phenomenon of human pregnancy impossible. Semiallogeneous nature, localization placenta, complex and heterogeneous cellular composition determines its multifaceted role in course physiological pregnancy, indicates importance studying this organ number reproductive pathologies. The purpose review was to analyze literature sources illustrating en...

Ghrelin, a GH-releasing acylated peptide, has been recently identified from the rat stomach. The purified peptide consists of 28 amino acids in which the serine 3 residue is n-octanoylated. Here we show that ghrelin messenger RNA and ghrelin peptide are present in the human as well as in rat placentae. In human placenta, ghrelin was detected by PCR at both first trimester and after delivery. Wh...