TRAINING PROGRAM OF GRADED EXERcise while breathing oxygen is employed in patients with pulmonary emphysema in whom physical unfitness has been induced by excessive rest. Dyspnea on exertion naturally leads to inactivity which in itself promotes weakness, cardiovascular insufficiency and certain adverse biochemical changes, such as loss of nitrogen, calcium and potassium. Although walking abili...

To the Editoij, "Indian Medical gazette." Sir,?Recently reading in the British Medical Journal the successful treatment of pneumonia by the inhalation of oxygen, it struck me that the gas might be useful in the collapse stage of cholera, and I therefore write to suggest to those who have an opportunity of obtaining the gas?the desirability of giving it a trial. In the case described by Dr. Hami...

During nitric oxide (NO) inhalation therapy, NO combines with deoxyhemoglobin to form nitrosyl hemoglobin (HbNO). We used electron spin resonance (ESR) spectroscopy to measure HbNO in arterial and mixed venous blood of normoxic and hypoxic sheep during NO inhalation. Our aim was to quantitatively measure HbNO levels in the blood during NO inhalation, because large amounts of HbNO reduce the oxy...

SUMMARY Cerebral blood flow, oxygen, glucose, lactate, and pyruvate metabolism were measured in 13 subjects with completed stroke. Cerebral blood flow and oxygen consumption were reduced, glucose consumption and pyruvate production were normal, and lactate production was increased, suggesting a shift from aerobic to anaerobic cerebral glycolysis. To test this hypothesis, cerebral blood flow and...

The regional cerebral metabolism-to-perfusion imbalance has been studied in the three main categories of cerebrovascular disorders in a chronic phase of the disease, using the non-invasive oxygen-15 inhalation technique. In patients presenting with a history of transient ischaemic attacks, regional defects in cerebral perfusion were greater than for the corresponding oxygen uptakes. Areas of re...