Hydatidiform mole (often referred to as molar pregnancy) is the most common disorder in a category of pathologies known as Gestational Trophoblastic Diseases that are associated with abnormal fertilization in pregnancy. Current practices in screening and monitoring during early pregnancy allow for better identification of hydatidiform mole, sometimes prior to the onset of significant symptoms.O...

BACKGROUND Hydatidiform mole is an important obstetric problem which can result in harmful and serious outcomes. In this study, an attempt was made to determine the proportion of hydatidiform mole in prenatal clinics of Iran University of Medical Sciences (IUMS) to find the precise frequency of this disease. METHODS Between January 2012 and January 2013, all women who immediately after positi...

Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pr...

a twin pregnancy with a coexisting complete hydatidiform mole and a healthy fetus (cmcf) is rare. here we report three cases of cmcf with different clinical courses but similar outcome without a surviving neonate. two women required uterine evacuation before 20 weeks of gestational age because of vaginal bleeding and medical complications and the other patient underwent termination of her pregn...

background: hydatidiform mole is an important obstetric problem which can result in harmful and serious outcomes. in this study, an attempt was made to determine the proportion of hydatidiform mole in prenatal clinics of iran university of medical sciences (iums) to find the precise frequency of this disease. methods: between january 2012 and january 2013, all women who immediately after positi...

objective(s)distinction of hydatidiform moles from non-molar specimens and subclassification of hydatidiform moles as complete and partial are important for clinical practice, but diagnosis based solely on histomorphology suffers from poor interobserver reproducibility. nowadays, pathologists rely on molecular techniques, however these methods are technically difficult, relatively expensive, an...

AIM To quantify and compare decidual leucocyte subpopulations in complete and partial hydatidiform molar pregnancy with those in normal early pregnancy. METHODS Decidual leucocytes were characterised using an avidin-biotin technique and a panel of monoclonal antibodies in formalin fixed, paraffin embedded decidual tissues from 10 normal first trimester pregnancy terminations and from 13 parti...

introduction: this study was performed to establish a complementary method to the diagnosis of complete hydatidiform mole and its differentiation from the other cases of gestational trophoblastic disease by measuring the total (alp) and placental alkaline phosphatase (plap) specific activity. materials and methods: serum and tissue extracts from 13 patients, 13 normal non-pregnant and 30 pregna...