BACKGROUND Photosensitivity has been reported in patients who were treated with vandetanib (ZD6474), an inhibitor of epidermal growth factor receptor, vascular endothelial growth factor receptor, and the RET (rearranged during transfection) kinases. OBSERVATIONS We describe the occurrence of cutaneous hyperpigmentation after photosensitivity in 2 patients who were treated with vandetanib. The...

Cutaneous hyperpigmentation is a common and well-defined side effect of many drugs, such as non-steroidal anti-inflammatory drugs, beta-blockers, and tetracyclines, but to the best of our knowledge there is no case of skin discoloration related to nebivolol in the literature. Presently described is lichenoid type cutaneous hyperpigmentation in a 46-year-old female patient. Hyperpigmentation eme...

To cite: Nestor LA, Flint S, Galvin S. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217545 DESCRIPTION A 62-year-old Caucasian woman was referred to dermatology by oral medicine regarding intra and extraoral hyperpigmentation which had developed gradually over the past year. Her only significant medical history was stage 4 colorectal carcinoma diagnosed 8 y...