Symptomatic hyperviscosity is a common clinical manifestation in patients with Waldenstr€ om macroglobulinaemia (WM) and high serum IgM levels. Prompt intervention is required to prevent catastrophic events, such as retinal or central nervous system bleeding. Identifying patients at high risk of symptomatic hyperviscosity might support the decision to treat asymptomatic patients before irrevers...

Symptomatic hyperviscosity is a common clinical manifestation in patients with Waldenström macroglobulinaemia (WM) and high serum IgM levels. Prompt intervention is required to prevent catastrophic events, such as retinal or central nervous system bleeding. Identifying patients at high risk of symptomatic hyperviscosity might support the decision to treat asymptomatic patients before irreversib...

Oncologic emergencies can present either as a progression of a known cancer or as the initial presentation of a previously undiagnosed cancer. In most of these situations, a very high degree of suspicion is required to allow prompt assessment, diagnosis, and treatment. In this article, we review the presentation and management of cardiovascular oncologic emergencies from primary and metastatic ...

semen hyperviscosity (shv) is one of the factors involved in deficiency in sperm function. this research aimed to evaluate seminal plasma total antioxidant capacity (tac) and malondialdehyde (mda) levels in infertile patients with hyperviscous and non-hyperviscous semen samples to understand whether hyperviscous semen is associated with oxidative damage in infertile subjects. in this cross sect...

Efficacy of plasma exchange in patients with systemic lupus erythematosus has not been supported by the results of the first non-controlled and retrospective studies. Nonetheless, they remain relevant for some selected patients with life-threatening manifestations and/or severe therapy-resistant manifestations. They can be used as an adjuvant therapy in combination with corticosteroids and, whe...

We introduce new resolution-aware dissipation mechanisms for CAM-SE (CAM with the spectral element dycore from HOMME) and evaluate their performance for a set of problems with locally refined grids. CAM-SE uses unstructured quadrilateral meshes with hyperviscosity for horizontal dissipation. The hyperviscosity operator requires a resolution-dependent coefficient. For variable-resolution grids, ...