Hypoglycemia is the major barrier for optimal glycemic control in patients on maintenance insulin therapy. It is widely known that good glycemic control leads to prevention of or delay in the development of microvascular complications, and can reduce macrovascular events. It is thought that hypoglycemia may predispose patients to cognitive deterioration and may negatively affect the cardiovascu...

Objective: The purpose of this particular study is to examine the incidence hypoglycemia in people who have diabetes type 2. Study Design: Cross-sectional Place and Duration: In department Medicine/ Endocrinology Allied Hospital, Faisalabad for duration from November 2021 April 2022. Methods: Overall, 86 patients both sexes were presented with type-2 mellitus. Among those as young 18 old 65. Be...

Hypoglycemia after ingestion of ethanolic beverages has been reported (1-4). In some cases (1, 2), hypoglycemia was attributed to the nonethanol ingredients in such mixtures as "smoke" and "solox" (methyl alcohol, and gasoline and ethyl acetate). Cummins, however, suggested that hypoglycemia might be caused by ethanol itself (3). He described a 6-year-old boy who had convulsions and hypoglycemi...

Permanent brain injury is a complication of recurrent hypoglycemia during development. Recurrent hypoglycemia also has adverse consequences on the neuroendocrine system. Hypoglycemia-associated autonomic failure, characterized by ineffective glucose counterregulation during hypoglycemia, is well described in children and adults on insulin therapy for diabetes mellitus. Whether recurrent hypogly...

Manifested hypoglycemia is relatively frequent cause of out-patient office visit at general practitioner, diabetologist and in severe cases represents emergent situation requiring transport to hospital and hospitalization. Severe and untreated hypoglycemia can even lead to death. The aetiology of hypoglycemia is variable, and includes drugs, insulinoma, liver failure, renal failure, hormonal de...

transient hyperinsutinism has been implicated in the prolonged hypoglycemia observed in small for gestational age or asphyxiated newborns. tiiesc infants are at high risk for severe and permanent brain damage, thus necessitating appropriate diagnosis and correct treatment. a term male asphyxiated small for gestation 30 day infant with long-standing hypoglycemia and intractable seizures was mana...

OBJECTIVE People with type 2 diabetes are at increased risk of age-related cognitive decline and dementia. Hypoglycemia is a candidate risk factor, but the direction of association between episodes of severe hypoglycemia and cognitive decline in type 2 diabetes remains uncertain. RESEARCH DESIGN AND METHODS In the Edinburgh Type 2 Diabetes Study, cognitive function was assessed in 831 adults ...

OBJECTIVE Although intensive glycemic control achieved with insulin therapy increases the incidence of both moderate and severe hypoglycemia, clinical reports of cognitive impairment due to severe hypoglycemia have been highly variable. It was hypothesized that recurrent moderate hypoglycemia preconditions the brain and protects against damage caused by severe hypoglycemia. RESEARCH DESIGN AN...

OBJECTIVE The aim of this study was to develop a partial closed-loop system to safely prevent nocturnal hypoglycemia by suspending insulin delivery when hypoglycemia is predicted in type 1 diabetes. RESEARCH DESIGN AND METHODS Forty subjects with type 1 diabetes (age range 12-39 years) were studied overnight in the hospital. For the first 14 subjects, hypoglycemia (<60 mg/dl) was induced by g...