INTRODUCTION Pulse oximetry (SpO2) measures oxygen saturation but not alveolar ventilation. Its failure to detect alveolar hypoventilation during sedated endoscopy under oxygen supplementation has been reported. The aim of this study was to measure the masking effect of oxygen supplementation in SpO2 when alveolar hypoventilation develops during sedated endoscopy. METHODS A total of 70 patien...

STUDY OBJECTIVE This two-part study was designed to determine the effect of supplemental oxygen on the detection of hypoventilation, evidenced by a decline in oxygen saturation (Spo(2)) with pulse oximetry. DESIGN Phase 1 was a prospective, patient-controlled, clinical trial. Phase 2 was a prospective, randomized, clinical trial. SETTING Phase 1 took place in the operating room. Phase 2 too...

Sleep apnea test (SAT) is a cost-effective approach to evaluate subjects without associated comorbidities suspected for obstructive sleep (OSA), disorder particularly common in obese subjects. The association of obesity with awake hypercapnia (carbon dioxide arterial pressure, PaCO2 ≥45 mmHg) defines the obesity-hypoventilation syndrome (OHS), which turn results increased morbidity and mortalit...

of 100% oxygen during induction and emergence is standard practice for the vast majority of anesthetists, our study reflects the impact of high intraoperative inspired oxygen in actual practice. The use of 100% oxygen for induction and emergence also likely had minimal effect on our results because the degree of atelectasis induced by administration of 100% oxygen for only a few minutes is rela...

1 Mokhlesi B, Kryger MH, Grunstein RR. Assessment and management of patients with obesity hypoventilation syndrome. Proc Am Thorac Soc 2008; 5: 218–225. 2 Subramanian S, Strohl KP. A management guideline for obesity–hypoventilation syndromes. Sleep Breath 1999; 3: 131–138. 3 Campo A, Frühbeck G, Zulueta JJ, et al. Hyperleptinaemia, respiratory drive and hypercapnic response in obese patients. E...

To the Editor: Alveolar hypoventilation in association with obesity was described first by Burwell' in 1956. In later years, many cases of this syndrome have been reported. A similar syndrome in nonobese subjects was recognized in 1965.2 By 1970, 30 cases, most of whom were men, had been reported." We wish to report a case of idiopathic hypoventilation in a young, thin woman. We shall point out...

Obesity hypoventilation syndrome (OHS) is commonly defined as a combination of obesity (body mass index (BMI) .30 kg?m), waking arterial hypercapnia (arterial carbon dioxide tension (Pa,CO2) .6.0 kPa (45 mmHg)) and sleepdisordered breathing. Essential to the diagnosis is exclusion of other causes of alveolar hypoventilation [1]. The lack of a standardised definition of OHS in general, and of OH...