The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the metastatic potential of tumors. To select antibodies targeting the varied functions of L1, we screened the Tomlinson library of recombinant human antib...

At least some animal species can generate neurons from mesoderm or endoderm, but the underlying mechanisms remain unknown. We screened for C. elegans mutants in which the presumptive mesoderm-derived I4 neuron adopts a muscle-like cell fate. From this screen, we identified HLH-3, the C. elegans homolog of a mammalian proneural protein (Ascl1) used for in vitro neuronal reprogramming, as require...

Tissue-specific heterogeneity among mammalian acetylcholinesterases (AChE) has been associated with 3* alternative splicing of the primary AChE gene transcript. We have previously demonstrated that human AChE DNA encoding the brain and muscle AChE form and bearing the 3* exon E6 (ACHE-E6) induces accumulation of catalytically active AChE in myotomes and neuromuscular junctions (NMJs) of 2and 3-...

In this paper we prove identities involving the classical Jacobi theta functions of the form ∑c(i1, i2, i3, i4)θ1(z|τ)1 θ2(z|τ)2 θ3(z|τ)3 θ4(z|τ)4 = 0 with c(i1, i2, i3, i4) ∈ K[Θ], where K is a computable field and Θ := { θ 1 (0|τ) : k ∈ N } ∪ { θ j (0|τ) : k ∈ N and j = 2,3,4 } . We give two algorithms that solve this problem. The second algorithm is simpler and works in a restricted input cl...

The title compound, [Zn{(CH3)2SO}6]I4, is a one-dimensional supra-molecular polymer along a threefold rotation axis of the space group. It is built up from discrete [Zn{(CH3)2SO}6](2+) units connected through non-classical hydrogen bonds to linear I4 (2-) polyiodide anions (C-H⋯I = 3.168 Å). The Zn(II) ion in the cation has an octa-hedral coordination geometry, with all six Zn-O bond lengths be...

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shallot (allium altissimum regel.) is a medicinal, industrial and perennial plant that has underground tubers. it is one of the most important allium species in iran, which normally grows in semi-cold to very cold highlands. because of being a wild plant, shallot is encounter with water deficit during its growth season. therefore evaluation of water requirement of shallot is important. in order...

The enzyme UGT2B7 is one of the most active UDP-glucuronosyltransferases (UGTs) involved in drug metabolism and in maintaining homeostasis of endogenous compounds. We recently reported the existence of 22 UGT2B7 mRNAs, two with a classic 5' region but alternative 3' ends namely UGT2B7_v5 (containing a novel terminal exon 6b) and _v7 (exon 5 excluded) that encode enzymatically inactive isoforms ...

The purpose of this presentation is to outline the Museum Multimedia (MM) experience in Russia. I am quite not sure wether all my colleagues experts and museum community in West Europe and America are intimately familiar with Russian experience in this sphere and I am pleased to have this opportunity to fill the gap. I will mainly focus on the general picture for some more reports with detailed...

Abstract. If a tensor with various symmetries is properly unfolded, then the resulting matrix inherits those symmetries. As tensor computations become increasingly important it is imperative that we develop efficient structure preserving methods for matrices with multiple symmetries. In this paper we consider how to exploit and preserve structure in the pivoted Cholesky factorization when appro...