HIV-1 drug resistance is a major clinical problem. Resistance is evaluated using in vitro assays measuring the fold change in IC(50) caused by resistance mutations. Antiretroviral drugs are used at concentrations above IC(50), however, and inhibition at clinical concentrations can only be predicted from IC(50) if the shape of the dose-response curve is also known. Curve shape is influenced by c...

Using the idea of ic-open sets, we introduce and investigate topological qualities an ic-closure, ic-interior, ic-limit points, ic-derived, ic-border, ic-frontier, ic-exterior a set. Introduce concepts "ic-continuous mappings," "ic-open "ic-irresolute "ic-totally continuous "ic-homeomorphism," then look into some properties these mappings

A major challenge for interdisciplinary teamwork on complex sustainability issues is the often-conflicting disciplinary perspectives and underlying values assumptions among collaborators. Interdisciplinary collaboration researchers practitioners therefore requires consciousness (IC): epistemological metaphysical understanding appreciation of one’s own others’ views their differences. Since it c...

The present study was designed to assess and compare three different formulations of the new Onderstepoort infectious coryza (IC) quadrivalent vaccine, which contain an NAD-independent strain of Avibacterium paragallinarum (previously known as Haemophilus paragallinarum), and a commercial IC vaccine, not containing an NAD-independent strain, for their safety and ability to protect chickens of v...

More than a decade of research in the field of thermal, motion, vibration and electromagnetic radiation energy harvesting has yielded increasing power output and smaller embodiments. Power management circuits for rectification and DC–DC conversion are becoming able to efficiently convert the power from these energy harvesters. This paper summarizes recent energy harvesting results and their pow...

This paper describes the development and preliminary testing of a robotic device to facilitate minimally invasive beating-heart intrapericardial interventions. We propose the concept of a subxiphoid-inserted mobile robot (HeartLander) with the ability to adhere to the epicardium, navigate to any location, and administer therapy under physician control. As compared to current laparoscopic cardia...

Ion chromatography (IC) presents new possibilities for assessing information about environmental samples, namely waters of various compositions, ranging from high-purity water to highly saline ones. Constant proportion between major ions present in seawater, has been assumed in the past, from which the first practical equation relating chlorinity and salinity has been developed, being later sub...