Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sweeping the world since end of 2019. The titer change antibodies against SARS-CoV-2 needs to be further clarified, clinical and preventive value still investigated. An enzyme-linked immunosorbent assay (ELISA) was established by coating with recombinant spike protein used detect serum immunoglobulin M (IgM) G (IgG) in disease 2019...

Polyclonal antibodies against kappa light chain are used to diagnose diseases producing free light chain. The kappa and lambda light chains are products of immunoglobulin synthesis and released into the circulation in minor amounts such as serum, cerebrospinal fluid, urine and synovial fluid in normal condition. The purpose of this study was the production and purification of polyclonal immunog...

The immune system may interplay between Chlamydia pneumoniae infection and coronary artery disease (CAD). Major histocompatibility complex genes regulate innate and adaptive immunity. Patients with CAD (n = 100) and controls (n = 74) were enrolled. Human leukocyte antigens (HLA-A, HLA-B, and HLA-DRB1), four lymphotoxin alpha single-nucleotide polymorphisms, and complement C4A and C4B allotypes ...

PURPOSE To evaluate type-specific antichlamydial antibody IgG in children with chronic follicular conjunctivitis. METHODS A total of 90 serum samples from juvenile patients with chronic follicular conjunctivitis were collected in the Southeastern Anatolian region of Turkey where trachoma is still endemic. These samples were investigated regarding Chlamydia trachomatis pooled serotype-specific...

BACKGROUND AND PURPOSE Previous studies have produced conflicting results regarding the putative association between anticardiolipin antibodies (aCL) and infarction in the general stroke population. These inconsistencies may be a function of sample size and methodological differences among the studies. The purpose of the present study, the largest case-control study of this issue to date, was t...

The prevalence of antibodies detected by serology against Toxoplasma gondii in Indonesia is quite high. Therefore further research concerning the antigen used is important to improve the quality of the assay being used with lower cost. An attempt to prepare T. gondii strain RH antigen followed by using it in the ELISA procedure for detecting IgG showed that there was no significant difference b...

BACKGROUND Whether serological evidence of prior infection with Chlamydia pneumoniae, herpes simplex virus type 1 (HSV-1), and cytomegalovirus (CMV) is associated with myocardial infarction (MI) and coronary heart disease (CHD) death remains a source of controversy. METHODS AND RESULTS We conducted a nested case-control study among participants in the Cardiovascular Health Study, a cohort stu...

Background—Whether serological evidence of prior infection with Chlamydia pneumoniae, herpes simplex virus type 1 (HSV-1), and cytomegalovirus (CMV) is associated with myocardial infarction (MI) and coronary heart disease (CHD) death remains a source of controversy. Methods and Results—We conducted a nested case-control study among participants in the Cardiovascular Health Study, a cohort study...

Antiphospholipid antibodies (APLA) may be detected in normal pregnancies and also may cause thrombosis, recurrent fetal loss, placental infarction and preeclampsia. In the present study the possible differences in APLA titer between healthy pregnant women and preeclampsia cases without history of thrombosis was examined. The APLA titer in 50 healthy pregnant women with 50 preeclampsia cases wit...