Granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. Granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. The etiopathogenesis of granulomas associated with malignancies is not clear but it may be because of an immunologic reaction to tumour ...

  Partially fed (4 -5 days) H .a. anatolicum (Iranian isolate) female adult ticks were used for preparation of antigens of midgut which are, the gut supernate antigen (GS), gut membrane antigen (GM), triton extracted gut membrane antigen ( TX-GM ) and sodium dodecyl sulphate treated Triton extracted gut membrane antigen (SDS-TX-GM). The New Zealand white rabbits were immunized with GS, GM, TX- ...

granulomatous response in association with breast cancer and within the cancer draining lymph nodes is an extremely rare phenomenon. granulomatous inflammation is an immune response commonly seen against infectious agents and certain non-neoplastic conditions. the etiopathogenesis of granulomas associated with malignancies is not clear but it may be because of an immunologic reaction to tumour ...

Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune responses against such neo-antigens may lead to the elimination or functional impairment of normal cells,...

background: cerebral malaria (cm) is one of the major causes of death in african populations infected with plasmodium falciparum. only 1% of infected subjects develop cm. the reasons for these differences are not fully understood, but it is likely that the host humoral response against blood-stage antigens plays a role in protection from malaria, although the precise targets and mechanisms medi...

coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...

one of the most common outcomes of pulp inflammation is periapical granuloma formation. existence of immune cells in these lesions showed involvement of both humoral and cellular immunity in the site. the presence of different antigens in the root canal causes production o various antibodies and consequent immunological reactions. different theories have been proposed on periapical cysts. the m...

background: tumor associated antigens can be viably used to enhance host immune response.objectives: the immunomodulatory effect of biogenic selenium nanoparticles (senps) was compared between treated and untreated mice with crude antigens of 4t1 cells.materials and methods: female inbred balb/c mice (60) were injected by cancinogenic 4t1 cells causing breast cancer. after 10 days, all tumor be...