I read a case report about Tuberculosis and fungal co-infection in a previously healthy patient published in Colomb Med (Cali) by Fontalvo et al.1, (http://colombiamedica.univalle.edu.co/index.php/ comedica/article/view/2271) and I would like to address some related comments. Frequently clinicians report adult cases of patients with opportunistic infections as disseminated tuberculosis and/or f...

Cytomegalovirus infections are widely distributed with a seroprevalence of up to 100%. The majority of the cases take a silent course or deal with unspecific clinical symptoms. Complications in immunocompetent patients are rare but may affect the liver and lead up to an acute organ failure. In this case report, we describe a 35-year-old immunocompetent female with an acute cytomegalovirus infec...

BACKGROUND Pneumocystis spp. are opportunistic pathogens that cause pneumonia in immunocompromised humans and animals. Pneumocystis colonization has also been detected in immunocompetent hosts and may exacerbate other pulmonary diseases. Surfactant protein A (SP-A) is an innate host defense molecule and plays a role in the host response to Pneumocystis. METHODS To analyze the role of SP-A in ...

Hand, foot and mouth disease most commonly occurs in children less than 10 years old, but can occur in immunocompetent adults. We describe a 37-year-old immunocompetent man who presented with multiple painful papules and vesicles on his palms and feet together with vesicles inside the mouth. Real-time polymerase chain reaction revealed Coxsackievirus A6 in the vesicle fluid from the feet, throa...

Isolated cerebellar cryptococcoma in an immunocompetent patient is a rare condition. We report a case of an immunocompetent adult with isolated cerebellar cryptococcoma. The patient presented with chronic headaches for one year and was found to have multiple cerebellar abscesses on imaging. Our patient underwent resection of the lesion and the cryptococcoma was subsequently diagnosed by histolo...

A 26-year-old female, immunocompetent, with dysmetria and dysarthria. Diagnostic imaging (Fig 1) demonstrated a cerebellar mass, with a pattern which may be associated to a tumor, although multiple hypointense centers surrounded by ring enhancement after gadolinium may suggest the possibility of many types of infectious lesions, including cryptococcoma. Histological analysis (Fig 2) confirmed t...

The granulomatous inflammation of tuberculosis usually involves the lungs and the hilar lymph nodes. Musculoskeletal tuberculosis (TB) occurs in 1-3% of patients with TB, while TB of the chest wall constitutes 1% to 5% of all cases of musculoskeletal TB. Furthermore, nowadays it is rarer to find extrapulmonary TB in immunocompetent rather that non-immunocompetent patients. The present case repo...

Diagnosis: Acute cytomegalovirus (CMV) infection in an immunocompetent host. This patient was admitted to the hospital, and serologic testing for CMV revealed positive IgM and IgG responses. PCR of a blood sample for CMV DNA revealed 3500 copies/mm. Because of her severe and prolonged symptoms, the patient received oral valgancyclovir (900 mg b.i.d.), with resolution of fever within 24 h after ...

Disseminated cryptococcosis is not common in immunocompetent persons. Here we report a case of disseminated cryptococcosis in an immunocompetent individual caused by Serotype B. Detailed case history with informed consent was taken followed by thorough investigation. A search was made on the Internet (Medline, ProQuest and Google) for similar findings. Cryptococcus gattii was isolated from bloo...

BACKGROUND Polyomavirus nephropathy has emerged as an important cause of graft loss in kidney transplant recipients. Polyomavirus rarely affects the native kidneys of an immunocompetent individual. Until now, polyomavirus nephropathy in native kidneys of an immunocompetent individual has not been reported, as far as we know. CASE REPORT A 34-year-old man was transferred from a local clinic to b...