Delayed or cellular hypersensitivity is the primary immunologic mechanism in the rejection of organ homografts. Mounting evidence implicates the small lymphocyte as the cell responsible for implementing this reaction. The immunologic role of the lymphocyte in the graft-versus-host reaction was first recognized by Simonsen (1957). He showed that if newborn or heavily irradiated mice are injected...

primary immunodeficiency diseases (pid) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. this study was designed to find out the most important origins and aspects of stressor in parents of pid patients.to assess the  impact of  psychiatric aspects in parents  of pid  patients, a valid and reliable questionnaire was compiled ba...

Neonatally thymectomized uretha~-treated Swiss mice inoculated repeatedly with competent lymphoid cells from the same random-bred strain developed a higher incidence of lung adenomas than that observed in thymectomized urethantreated controls. The immunologic impairment and pathologic findings noted in the inoculated animals were more severe than those observed in neonatally thymectomized contr...

Food allergy is defined as reaction to a food which has an immunologic mechanism. Its prevalence is increasing in children globally and is therefore of increasing clinical importance. A useful clinical approach is to distinguish food allergic reactions by the timing of clinical reaction in relation to food exposure and classified as immediate (generally IgE-mediated) and delayed (generally non-...

Significant advances have been presented in the last decades field of biomedical analysis and sensing, especially pertaining to routine procedures based on immunologic nucleic acids, including enzyme-linked immunosorbent assay (ELISA) real-time polymerase chain reaction (RTq-PCR). Despite their efficiency, some limitations such as reagent stability availability, cost cumbersome still limit furt...

The prevalence of endocrinopathies during myasthenia is relatively common. association with dysthyroidism can make the diagnosis these two conditions difficult, because similaritý some clinical signs. Several disorders specifically thyroid immunologic origin have beeń reported in myasthenic patients. This relationship remains poorly elucidated, but an cross-reaction between neuromuscular juncti...

Neonatally thymectomized uretha~-treated Swiss mice inoculated repeatedly with competent lymphoid cells from the same random-bred strain developed a higher incidence of lung adenomas than that observed in thymectomized urethantreated controls. The immunologic impairment and pathologic findings noted in the inoculated animals were more severe than those observed in neonatally thymectomized contr...

The apparent simultaneous presence of surface markers characteristic of both B and T cells is a phenomenon being described with increasing frequency in patients with chronic lymphocytic leukemia (CLL). We describe a patient with CLL whose B lymphocytes possessed surface immunoglobulin reactive with neuraminidase-treated sheep erythrocytes (SRBCs) and produced E rosette formation. Cytofluorograp...