نتایج جستجو برای: immunopotentiation

تعداد نتایج: 85  

2008
Bidhan C. Bandyopadhyay Lina Chakrabarti Mrinal. K. Poddar

Activation or inhibition of hypothalamic GABAergic activity and immunopotentiation or immunosuppression during aging depends on the variation of the amount of dietary protein as well as the duration of its supplementation. Here we evaluate the effect of low (5%) and high (40%) protein diet on the functional state of hypothalamic GABA receptor in the aging brain in albino rats. Consumption of lo...

Journal: :Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2010
Sivagurunathan Moni Sivakumar Natarajapillai Sukumaran Loganathan Nirmala Rathinavel Swarnalakshmi Botta Anilbabu Lakshmanan Siva Jayaraman Anbu Thukani Sathanantham Shanmugarajan Velayudam Ravichandran

BACKGROUND/PURPOSE The purpose of this research was to develop an alternative adjuvant for hepatitis B vaccine (HBsAg) that elicits a long-lasting immune response after a single administration. In this study, the suitability of Poly (D, L)-lactide-co-glycolic acid (PLGA), Poly lactic acid (PLA) and Chitosan polymers as adjuvants for HBsAg were investigated. METHODS We used solvent evaporation...

2010
H. Keipp Talbot Michael T. Rock Casey Johnson Lynda Tussey Uma Kavita Anita Shanker Alan R. Shaw David N. Taylor

BACKGROUND Currently controversy exists about the immunogenicity of seasonal trivalent influenza vaccine in certain populations, especially the elderly. STF2.4×M2e (VAX102) is a recombinant fusion protein that links four copies of the ectodomain of influenza virus matrix protein 2 (M2e) antigen to Salmonella typhimurium flagellin, a TLR5 ligand. The objectives of this study were to assess the f...

Journal: :Journal of immunology 2016
Melissa A Kachura Colin Hickle Sariah A Kell Atul Sathe Carlo Calacsan Radwan Kiwan Brian Hall Robert Milley Gary Ott Robert L Coffman Holger Kanzler John D Campbell

Nanoparticulate delivery systems for vaccine adjuvants, designed to enhance targeting of secondary lymphoid organs and activation of APCs, have shown substantial promise for enhanced immunopotentiation. We investigated the adjuvant activity of synthetic oligonucleotides containing CpG-rich motifs linked to the sucrose polymer Ficoll, forming soluble 50-nm particles (DV230-Ficoll), each containi...

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