food intake of rats increases during pregnancy. this requires changes in the structure of the small intestine to absorb additional food. the aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. duodenum, jejunum and ileum of 18 pregnant sprague-dawley rats (day 7, 14 and 21 of pregnancy) were collected. villous height a...

Immunoproliferative small intestinal disease (originally called Mediterranean lymphoma and subsequently alpha chain disease) is a slowly progressive low grade primary small intestinal B-cell lymphoma characterized by the synthesis of a truncated alpha heavy chain without light chain by the neoplastic cells. The histological features of IPSID and low grade primary gastric B-cell lymphoma are clo...

INTRODUCTION Two decades ago tropical sprue, Immunoproliferative Small Intestinal Disease (IPSID) and infections were common causes of malabsorption in India. It is possible that implementation of preventive health measures and improved sanitation may have changed the spectrum of disorders causing malabsorption. The aim of this study therefore was to assess the spectrum of malabsorption seen at...

A group of 21 patients with immunoproliferative small intestinal disease (IPSID), 10 with alpha heavy chain paraproteinaemia and 11 without it, were HLA typed. The results were compared with 35 disease controls and 120 normal controls. A significant increase of Aw19 and B12 antigens was noted among the patients compared with the control subjects. The high rate of association of both AW19 and B1...

â  â  background eosinophilic gastroenteritis (eg) is a rare inflammatory disorder of the gastrointestinal (gi) tract. there have been several case series of patients with eg from the western world and east asia. however, there has not been a report of patients with eg from the middle east region. the aim of this study is to describe clinical characteristics and treatment response in a series o...

Analysis of DNA from the mucosal tissue of three patients with immunoproliferative small intestinal disease (IPSID) and alpha chain disease, two of whom had early stage disease responsive to antibiotics, showed monoclonal heavy and light chain gene rearrangements in all cases. These findings suggest that IPSID is neoplastic even in its early stages, but that the neoplastic cells respond to norm...

Background. a-IFN is reported to be an effective treatment for a number of lymphoproliferative diseases. Little information is available at present on its effect in unaggressive immunoproliferative disorders. Study design and results. In a prospective non randomized study, 57 patients with IgG or IgA MGUS, smouldering myeloma or stage I MM treated with a-IFN (3 MU 3 times a week for at least 6 ...

background celiac disease is an autoimmune mediated small intestine inflammation which is occurred due to hypersensitivity reaction to gluten and related proteins in diet in genetically predisposing individuals. prevalence of celiac among the population is about 0.5 – 1 % in most countries. frequency of celiac disease in children is a subject of few research .in this study, we aim to determine ...

background: coeliac disease is triggered by ingestion of gluten-containing cereals in genetically susceptible subjects. the aim of the study was to analyze correlation between serum antiendomysial antibody and antiglidin antibody and the grade of pathology in small intestine mucosa in children with celiac disease. materials and methods: this cross-sectional analysis was carried out in a group o...