نتایج جستجو برای: immunoregulatory activity
تعداد نتایج: 1137202 فیلتر نتایج به سال:
Melatonin has been shown to regulate several immune functions, and some authors showed that leukocytes are also able to produce the indolamine. In fact, it seems to take part in some immunoregulatory axis, including that related to interferon (IFN) production. So, we evaluated the rate of tryptophan consumption and melatonin and serotonin production in peritoneal cavity-isolated macrophages and...
Hypomorphic mutations of the RAG genes in humans are associated with a spectrum of clinical and immunologic presentations that range from T(-) B(-) severe combined immune deficiency (SCID) to Omenn syndrome. In most cases, residual V(D)J recombination activity allows for development of few T-cell clones, which expand in the periphery and infiltrate target organs, resulting in tissue damage. Inv...
The effect of carbohydrate moiety structure on the immunoregulatory activity of lactoferrin in vitro
human peripheral blood monocytes have been found to undergo a transitory state of high accessory activity before they fully become macrophages. time kinetics were done to follow this accessory potential. studying the regulation of accessory activity, we have found that monocyte derived accessory cells (m-ac) pass through two phases of development, both of which are adversely controlled by cycli...
PROBLEM to better understand the immunoregulatory properties of trophoblasts, we have searched for small immunologically active carbohydrates derived from intact trophoblast-like cells. METHOD OF STUDY using solid phase extraction coupled with HPLC and mass spectrometry methods, we have characterized a low molecular weight carbohydrate-rich fraction associated with JEG-3 cells. We have also t...
The development of human T cell hybridomas secreting immunoregulatory molecules has been an area of recent intense interest and investigation. Functional hybrids derived from both normal and malignant human T cells have been developed. These hybrids have been demonstrated to secrete interleukin 2 (IL-2) 1 (1), killer helper factor (2), and factors that help or suppress immunoglobulin production...
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