The measurement of in vivo intramuscular pressure (IMP) has recently become practical and IMP appears well correlated with muscle tension. A numerical model of skeletal muscle was developed to examine the mechanisms producing IMP. Unipennate muscle is modelled as a two-dimensional material continuum that is incompressible and nonlinearly anisotropic. The finite element technique is used to calc...

IMP-minimax is the analog to minimax for games with imperfect information, like card games such as bridge or poker. It computes an optimal strategy for the game if the game has a single player and a certain natural property called perfect recall. IMP-minimax is described fully in a companion paper in this proceedings. Here we introduce an algorithm IMP-alpha-beta that is to IMP-minimax as alpha...

Sexual differentiation in Bombyx mori is controlled by sex-specific splicing of Bmdsx, which results in the omission of exons 3 and 4 in a male-specific manner. In B. mori, insulin-like growth factor II mRNA-binding protein (Imp) is a male-specific factor involved in male-specific splicing of Bmdsx. Male-specific Imp mRNA results from the male-specific inclusion of exon 8. To verify the link be...

Sjøgaard, Gisela, Bente R. Jensen, Alan R. Hargens, and Karen Søgaard. Intramuscular pressure and EMG relate during static contractions but dissociate with movement and fatigue. J Appl Physiol 96: 1522–1529, 2004. First published December 5, 2003; 10.1152/ japplphysiol.00687.2003.—Intramuscular pressure (IMP) and electromyography (EMG) mirror muscle force in the nonfatigued muscle during static...

Insulin-like growth factor-II mRNA-binding protein 3 (IMP-3) is an RNA-binding protein expressed in multiple cancers, including melanomas. However, the expression of IMP-3 has not been investigated in acral lentiginous melanoma (ALM). This study sought to elucidate its prognostic value in ALMs. IMP-3 expression was studied in 93 patients diagnosed with ALM via immunohistochemistry. Univariate a...

Pseudomonas aeruginosa (PA) plays plays an important role in nosocomial infection. To explore the heteroresistance of PA to imipenem (IMP), we detected the sensitivity of 140 strains of PA to IMP using the KB method and VITEK method. Combined with resistance mutation analysis, the heteroresistance of PA to IMP was determined. Whilst, the double disk synergy test and SYBGreen RT-PCR for efflux p...

Macromolecules are transported between the cytoplasm and the nucleoplasm of eukaryotic cells through nuclear pore complexes (NPCs). Large (more than approximately 40 kDa) transport cargoes imported into the nucleus typically form a complex with at least one soluble transport cofactor of the importin (Imp) beta superfamily. Many cargoes require an accessory cofactor, Imp alpha, which binds to Im...

20 We present IMP, an automated pipeline for reproducible integrated analyses of coupled 21 metagenomic and metatranscriptomic data. IMP incorporates preprocessing, iterative co22 assembly of metagenomic and metatranscriptomic data, analyses of microbial community 23 structure and function as well as genomic signature-based visualizations. Complementary use 24 of metagenomic and metatranscripto...

A human placental soluble "high Km" 5'-nucleotidase has been separated from "low Km" 5'-nucleotidase and nonspecific phosphatase by AMP-Sepharose affinity chromatography. The enzyme was purified 8000-fold to a specific activity of 25.6 mumol/min/mg. The subunit molecular mass is 53 kDa, and the native molecular mass is 210 kDa, suggesting a tetrameric structure. Soluble high Km 5'-nucleotidase ...

GOALS To examine the utility of integrated molecular pathology (IMP) in managing surveillance of pancreatic cysts based on outcomes and analysis of false negatives (FNs) from a previously published cohort (n=492). BACKGROUND In endoscopic ultrasound with fine-needle aspiration (EUS-FNA) of cyst fluid lacking malignant cytology, IMP demonstrated better risk stratification for malignancy at app...