Purpose – This paper aims to describe computer-aided design and rapid prototyping (RP) systems for the preoperative planning and fabrication of custom-made implant. Design/methodology/approach – A patient with mandible defect underwent reconstruction using custom-made implant. 3D models of the patient’s skull are generated based on computed tomography image data. After evaluation of the 3D reco...

Immediate postextraction implant placement in the areas of multiradicular teeth is a difficult procedure in view of having to place the implant in an ideal position without jeopardizing its initial stability. The surgeon often faces the problem of directing the initial osteotomy in the medial portion of the alveolus with the difficulty of engaging the inter-radicular septum of the extraction so...

The osseointegration and long-term success of bone-interfacing implants are dependent on mechanical stability of the implant relative to host bone during the early healing period. The geometric design of an implant surface may play an important role in affecting early implant stabilization, possibly by influencing tissue healing dynamics. In this study, we compared the early tissue healing resp...

INTRODUCTION Long-term success of load-bearing implants require solid fixation of the implant to the host bone by the process of osseointegration. Osseointegration is achieved by the growth and mineralization of bone tissue onto and into the textured surface of implants. According to current theories on tissue differentiation, peri-implant tissue formation and subsequent mineralization are depe...

The restoration of extensive zygomatic complex defects is a surgical challenge owing to the difficulty of accurately restoring the normal anatomy, symmetry, proper facial projection and facial width. In the present study, an extensive post-traumatic zygomatic bone defect was reconstructed using a custom-made implant that was made with a selective laser melting (SLM) technique. The computer-desi...

We present a software planning tool that provides intuitive visual feedback for finding suitable positions of hearing implants in the human temporal bone. After an automatic reconstruction of the temporal bone anatomy the tool pre-positions the implant and allows the user to adjust its position interactively with simple 2D dragging and rotation operations on the bone's surface. During this proc...

This paper presents rapid prototyping and reverse engineering techniques applied to create an implant for the surgical reconstruction of a large cranial defect. A series of computed tomography (CT) images was obtained and purpose built software was used to extract the cranial geometry in a point cloud. The point cloud produced was used for: (a) the creation of a stereolithographic (STL) physica...

Traditional knee replacement designs utilize multiple discrete radii to define the sagittal plane curvature of the femoral component (Fig. 1). This geometry was derived to replicate the function of the natural knee joint. The broader distal radius articulating against a relatively congruent tibial insert provides increased constraint and reduced contact stress in the range of flexion used for h...

Modulation of macrophage polarization and prevention of CCL2-induced macrophage chemotaxis are emerging strategies to reduce wear particle induced osteolysis and aseptic total joint replacement loosening. In this study, the effect of continuous IL-4 delivery or bioactive implant coating that constitutively releases a protein inhibitor of CCL2 signaling (7ND) on particle induced osteolysis were ...