We have determined the hydrogen-bond geometry in liquid water from 0 to 80 degrees C by combining measurements of the proton magnetic shielding tensor with ab initio density functional calculations. The resulting moments of the distributions of hydrogen-bond length and angle are direct measures of thermal disorder in the hydrogen-bond network. These moments, and the distribution functions that ...

The X-ray structure of the homodimeric chaperone CesT is the only structure among the type three secretion system (TTSS) chaperones that shows a domain swap. This swap has potential importance for the mechanism of effector translocation through a TTSS. Here we present two nuclear magnetic resonance strategies exploiting pre-existing structural models and residual dipolar couplings (RDCs), which...

Standard methods for estimating the effect of a time-varying exposure on survival may be biased in the presence of time-dependent confounders themselves affected by prior exposure. This problem can be overcome by inverse probability weighted estimation of Marginal Structural Cox Models (Cox MSM), g-estimation of Structural Nested Accelerated Failure Time Models (SNAFTM) and g-estimation of Stru...

past earthquakes have demonstrated that old rc bridges may be seismically vulnerable. bridge responses during the last decades illustrated the necessity of the seismic assessment of bridges especially those which were designed with old codes. in this research an existing concrete bridge representative of the most common bridges in the highway system in iran are studied. push over and nonlinear ...

this paper examines differences in performances of a range of torsionally stiff and flexible single story buildings designed with the provisions of iranian standard 2800. seismic nonlinear dynamic time history behavior of eight building models subjected to seven horizontal bi-directional design spectra compatible ground motions are investigated. these models cover a wide range of very torsional...