Insect bite hypersensitivity (IBH) in horses is a seasonal, IgE-mediated, pruritic skin disorder primarily caused by Culicoides spp. We hypothesize that a mixed Th2/Th1-type immune status, off season, alters into Th2-dominated immune reactivity in the skin of IBH-affected ponies in the IBH season. To study these immune response patterns Culicoides-specific IgE levels, skin histopathology and cy...

Pidcoke HF, Baer LA, Wu X, Wolf SE, Aden JK, Wade CE. Insulin effects on glucose tolerance, hypermetabolic response, and circadian-metabolic protein expression in a rat burn and disuse model. Am J Physiol Regul Integr Comp Physiol 307: R1–R10, 2014. First published April 23, 2014; doi:10.1152/ajpregu.00312.2013.—Insulin controls hyperglycemia after severe burns, and its use opposes the hypermet...

Insect bite hypersensitivity (IBH) is the most common allergic disease present in horses worldwide. It has been shown that IBH is under genetic control, but the knowledge of associated genes is limited. We conducted a genome-wide association study to identify and quantify genomic regions contributing to IBH in the Dutch Shetland pony population. A total of 97 cases and 91 controls were selected...

background: the over-expression of recombinant proteins in large amount is important for production of therapeutic proteins and structural study. there are several systems for expression of recombinant proteins. one of the most relevant expression systems is escherichia coli (e. coli). although this organism has many advantages, most of recombinant proteins expressed in e. coli hosts form inclu...

The purpose of this study was to examine the effects of training with intermittent breath holding (IBH) on respiratory parameters, arterial oxygen saturation (SpO2) and performance. Twenty-eight fin-swimming athletes were randomly divided into two groups and followed the same training for 16 weeks. About 40% of the distance of each session was performed with self-selected breathing frequency (S...

Equine insect bite hypersensitivity (IBH), commonly known as sweet itch or summer eczema, is a frustrating recurrent skin disease in the equine industry involving an immune reaction to the bites of Culicoides spp. midges. To investigate the impact of IBH in the field, an exploratory pilot study was conducted with equine stakeholders in one region of central England. Nine semi-structured, face-t...

A recent framework inspired by phenomenological philosophy, dynamical systems theory, embodied cognition and robotics has proposed the interactive brain hypothesis (IBH). Whereas mainstream social neuroscience views social cognition as arising solely from events in the brain, the IBH argues that social cognition requires, in addition, causal relations between the brain and the social environmen...

1. THE EXISTENCE OF DENTISTS Dr. Leek, the author of these arguments states that the specialization of Hesy-Re, an Ancient Egyptian physician said to be a dentist by many Egyptologists, is doubted by some others. He contends that his title 'wr ibh swnw', translated Chief of Dental Physicians by Junker Jonckheere4 and Lefebvre" could be an obscure non-medical attribution. This purely philologica...