Gilbert’s syndrome is a genetic disorder characterised by non-hemolytic unconjugated hyperbilirubinemia. It caused mutations in the UGT1A1 gene which codes for enzyme uridine diphosphate glucoronosyl transferase-1, conjugates bilirubin excretion. Affected individuals are usually asymptomatic apart from mild jaundice and investigations reveal isolated indirect This may be exacerbated face of env...

background: sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood ph in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and hematolog...

introduction autoimmune haemolytic anemia (aiha) is a complex process characterized by an immune reaction against red blood cell self-antigens. the analysis of specimens, drawn from patients with cold auto-immune hemolytic anemia is a difficult problem for automated hematology analyzer. this paper was written to alert technologists and pathologists to the presence of cold agglutinins and its ef...

life-long red blood transfusion remains the main treatment for severe thalassemia. the development of hemolytic alloantibodies and erythrocyte autoantibodies complicated transfusion therapy in thalassemia patients. the frequency causes and prevention of this phenomenon among 80 transfused thalassemia patients were evaluated in ali asghar children's hospital during 1998-2004 in a cross-sectional...

nine hundred and twelve, consecutive patients attended various clinics of isfahan university for various complains have been evaluated for a.s.o. titers among whom 172 has positive nasopharyngeal cultures for type a, b hemolytic streptococcus. all of the patients with positive cultures have a.s.o. titers of above 333 todd’s unit, while with exception of 22 cases all of the others had values of ...

It has been shown that patients with rheumatic fever continue to produce antibodies to hemolytic streptococcus for months after the subsidence of an apparently transient respiratory infection. The various clinical types of rheumatic fever are accompanied by characteristic types of antibody response. In monocyclic attacks with acute onset, a period of severe illness, and relatively rapid recover...

Dear Editor, Clofibrate is an activator of peroxisome proliferators-activated receptors (PPARS). This agent has been used for decreasing lipid levels in adults for years.1,2 It is also a glucuronyl transferase inducer which may increase bilirubin conjunction and excretion and not only has a therapeutic effect on hyperbilirubinemia in term neonates but also prevents hyperbilirubinemia in preterm...

The article presents the results of a clinical and bacteriological assessment pharmacological efficacy 1,3-diethylbenzimidazolium triiodide in chronic compensated tonsillopharyngitis. As result 10-day course treatment, an improvement status patients was achieved, as well significant positive effect on composition pharyngeal microbiocenosis. In particular, content Staphylococcus aureus, β-hemoly...

background and objective: hemolytic uremic syndrome (hus) is the most prevalent cause of children renal insufficiency which in many cases (90%) occurs following diarrhea. hemolytic microangiopathic anemia, thrombocytopenia, and renal insufficiency are main symptoms of hemolytic uremic syndrome. this study aims to consider the relationship between pathologic data of nephro-biopsy and laboratory ...

introduction methylene blue was first described for the treatment of methemoglobinemia but practical usage of the compound for surgical purpose is common. the aim of this report is to describe a case of hemolysis in neonatal period as a potential hazard of methylene blue toxicity without presence of g6pd deficiency. case presentation in october 2015, a 36-week ga female infant with 2.05 kg weig...