introduction: several mehods have been proposed to alleviate pain after hysterectomy. pre-emptive analgesia has been used to relieve pain following abdominal hysterectomy with conflicting results. this study was performed to evaluate the efficacy of pre-incision skin infiltration of lidocaine in relieving postoperative pain in patients undergoing abdominal hysterectomy.  methods: 60 patients wi...

BACKGROUND AND OBJECTIVES Serious functional and structural alterations of gastrointestinal tract are observed in failure of blood supply, leading to gastrointestinal dismotility. Activation of opioid receptors provides cardioprotective effect against ischemia-reperfusion (I/R) injury. The aim of the present study was to determine whether or not remifentanil could reduce I/R injury of small int...

Objective(s): Crocus sativus (saffron) has been widely used in traditional medicine. It has also been found to possess many beneficial properties in modern medicine. The most important ingredients of saffron are crocin, crocetin, safranal, and picrocrocin. This study evaluated the protective effects of crocin against the inflammation, oxidative stress, and functional disturbances of the kidney ...

objectives:the aim of the present study was to assess the analgesic efficacy of iv ketamine injection inaddition to nephrostomy tract infiltration of ketamine – bupivacaine on postoperative pain relief after tubeless percutaneous nephrolithotomy (pcnl). patients and methods: patients (n = 100), with renal stone who were candidates for pcnl were randomized to five groups with 20 cases in each: g...

BACKGROUND AND AIMS Local infiltration of the surgical wound is one of the important components of multimodal analgesia for post-operative pain relief. This study determines the post-operative analgesic effect of addition of dexmedetomidine to bupivacaine for local infiltration of the surgical wound. METHODS Sixty women belonging to American Society of Anesthesiologists' Grade 1 or 2 posted f...

conclusions patients in the bupivacaine infiltration and caudal block groups had less postoperative pain than those in the acetaminophen group and received lower amount of meperidine. we concluded that in children, bupivacaine infiltration and caudal block with bupivacaine produce better analgesia than suppository acetaminophen. it seems that bupivacaine infiltration is better than caudal block...

BACKGROUND Postoperative pain after total knee arthroplasty (TKA) can be difficult to manage and may delay recovery. Recent studies have suggested that periarticular infiltration with local anesthetics may improve outcome. METHODS 80 patients undergoing TKA under spinal anesthesia were randomized to receive continuous femoral nerve block (group F) or peri- and intraarticular infiltration and ...