crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

background: there is evidence that pulmonary function abnormalities are present in patients with inflammatory bowel disease (ibd). the aim of this case-control study was to assess the frequency of pulmonary dysfunction in patients with ibd. materials and methods: pulmonary function of 37 patients with ibd (8 with cd and 29 with uc) without any known pulmonary disease was tested by body-box plet...

background inflammatory bowel disease (ibd) may begin as early as the first year of life. the objective of the present study was to determine the characteristics and clinical course of children with early-onset ibd. materials and methods the records of patients with ibd admitted to children medical center hospital during 2003-2006 were screened for those with disease onset before the first year...

background worldwide, the incidence of inflammatory bowel disease (ibd) is increasing. this study aims to evaluate the diagnostic value of two serological markers, atypical perinuclear anti-neutrophil cytoplasmic antibodies (atypical-p-anca) and anti-saccharomyces cerevisiae antibodies (asca), with the intent to determinetheir relationship to ulcerative colitis (uc) and crohn's disease (cd), in...

background and aims: in diagnosing inflammatory bowel disease, one of diagnostic way is upper gastrointestinal endoscopy, which helps in differential diagnosis of unspecified colitis as well. the aim of this study was to investigate the necessity of upper gastrointestinal endoscopy in patients with inflammatory bowel disease.   materials and methods: in this descriptive cross-sectional study, 3...

Background: Inflammatory bowel disease (IBD) is a group of disorders that cause chronic inflammation (pain and swelling) in the intestines. IBD includes Crohn’s disease and ulcerative colitis. Both types affect the digestive system. The study aims to compare coping strategies in people with inflammatory bowel disease and healthy people, according to internal and external sources of health contr...

fecal calprotectin is released in colon by activated neutrophils. investigation of diagnostic application of determination of fecal calprotectin levels is considered by many researchers to compare between different colorectal diseases like irritable bowel syndrome (ibs) and inflammatory bowel diseases (ibd). due to the effect of nutrition habits on the inflammatory processes of bowel, the main ...