introduction and aims: microscopic colitis has been generally recognized as lymphocytic colitis and collagenous colitis: two inflammatory diseases of large intestine without a definite origin. the colon appears normal by colonoscopy. so, biopsy of the colonic mucosa is mandatory for diagnosis. materials and methods: as a descriptive design we assessed epidemiological, clinical and laboratory fi...

background : the incidence of inflammatory bowel disease (ibd) may have changed over time. the incidence and prevalence of ibd appears to be lower in asia and south america. although once believed to be infrequent in iran, there has been a rising trend in ibd over the past two decades. however, in iran there is no data about the incidence and prevalence of ibd. materials and methods : â demogra...

aim : the present study evaluated the association between g241r and k469e polymorphisms of intercellular adhesion molecule 1 gene and inflammatory bowel disease in iranian population.   background : inflammatory bowel disease including ulcerative colitis and crohn’s disease, is a chronic idiopathic inflammatory disease of the gastrointestinal tract. there are two single base polymorphisms of in...

pelvic inflammatory disease (pid) is a rare complication of transvaginal oocyte retrieval. it may result in failure of assisted reproductive techniques (art). during a 7 years period, 5958 transvaginal ultrasound-guided oocyte retrievals resulted in 10 cases of acute pid. eight out of 10 patients were diagnosed infertile because of endometriosis. two patients had mild ovarian, 3 had stage iii, ...

crohn’s disease (cd) is rarely presented with lower gi bleeding (lgib) which eludes the clinician. a 25-year-old lady with severe rectorrhagia was presented with no history of constipation, diarrhea or abdominal pain. colonoscopy revealed ulcers in the rectum, sigmoid colon, and terminal ileum. crohn’s pathologic features were detected in the terminal ileum. the bleeding was controlled via supp...

roaccutaneâ® (isotretinoin) is used for the treatment of severe forms of acne resistant to adequate standard therapy. inflammatory bowel disease (ibd) is described as a possible adverse drug reaction in the product information of isotretinoin. in a case study, we report the case of a 30 year old woman with a history of bloody diarrhea, abdominal pain and severe folliculitis/acne which had been ...

background: fecal calprotectin (fc) has been suggested as a noninvasive substitute marker to determine the degree of intestinal inflammation in patients with inflammatory bowel disease (ibd). the aim of this study was to compare fc levels in ibd and irritable bowel syndrome (ibs), to show its discriminative value and relationship with clinical disease activity in patients with ibd. materials an...

μalakoplakia is a rare inflammatory condition of the urogenital tract. the most frequently affected organ is urinary bladder. this condition has features of a granulomatous inflammation, the pathogenesis of which is not well understood. in this study, we presented a case of urinary bladder malakoplakia associated with advanced obstructive uropathy and renal failure.

In this review we consider the current evidence base for treatments in inflammatory eye disease, and in particular uveitis, from a historical perspective. We consider the challenges that have traditionally hindered progress in inflammatory eye disease including small target populations, heterogeneous disease groups, poorly defined phenotypes, diagnostic inconsistency, subjective outcome measure...