نتایج جستجو برای: influenza a h7n9 virus
تعداد نتایج: 13592173 فیلتر نتایج به سال:
Monitoring Avian Influenza A(H7N9) Virus through National Influenza-like Illness Surveillance, China
In China during March 4-April 28, 2013, avian influenza A(H7N9) virus testing was performed on 20,739 specimens from patients with influenza-like illness in 10 provinces with confirmed human cases: 6 (0.03%) were positive, and increased numbers of unsubtypeable influenza-positive specimens were not seen. Careful monitoring and rapid characterization of influenza A(H7N9) and other influenza viru...
Letters Virus-host interactions and the unusual age and sex distribution of human cases of influenza A(H7N9) in China, April 2013 Over the past two weeks, Eurosurveillance has published several timely papers related to the emergence of a new influenza A(H7N9) virus affecting humans in China [1-3]. Genetic studies by Kageyama et al. [1] and Jongens et al. [2] assessed evidence in the genome for ...
BACKGROUND The first human infections of novel avian influenza A(H7N9) virus were identified in China in March 2013. Sentinel surveillance systems and contact tracing may not identify mild and asymptomatic human infections of influenza A(H7N9) virus. OBJECTIVES We assessed the seroprevalence of antibodies to influenza A(H7N9) virus in three populations during the early stages of the epidemic....
H7N9 avian influenza is an emerging viral disease in China caused by avian influenza A (H7N9) virus. We investigated host cytokine and chemokine profiles in serum samples of H7N9 patients by multiplex-microbead immunoassays. Statistical analysis showed that IP-10, IL-6, IL-17, and IL-2 were increased in H7N9 infected patients. Furthermore, IL-6 and the chemokine IP-10 were significantly higher ...
BACKGROUND On March 30, 2013, a novel avian influenza A H7N9 virus that infects human beings was identified. This virus had been detected in six provinces and municipal cities in China as of April 18, 2013. We correlated genomic sequences from avian influenza viruses with ecological information and did phylogenetic and coalescent analyses to extrapolate the potential origins of the virus and po...
Low immunogenicity predicted for emerging avian-origin H7N9 Implication for influenza vaccine design
950 Human Vaccines & Immunotherapeutics Volume 9 Issue 5 *Correspondence to: Anne S. De Groot; Email: [email protected] Submitted: 04/03/13; Revised: 05/03/13; Accepted: 05/04/13 http://dx.doi.org/10.4161/hv.24939 a new avian-origin influenza virus emerged near shanghai in February 2013, and by the beginning of May it had caused over 130 human infections and 36 deaths. Human-to-human transmissi...
In spring 2013, influenza A(H7N9) virus was isolated from an apparently healthy tree sparrow in Chongming Dongping National Forest Park, Shanghai City, China. The entire gene constellation of the virus is similar to that of isolates from humans, highlighting the need to monitor influenza A(H7N9) viruses in different species.
Compounds that target the cellular factors essential for influenza virus replication represent an innovative approach to antiviral therapy. Sp2CBMTD is a genetically engineered multivalent protein that masks sialic acid-containing cellular receptors on the respiratory epithelium, which are recognized by influenza viruses. Here, we evaluated the antiviral potential of Sp2CBMTD against lethal inf...
An avian-origin influenza A (H7N9) virus was a cause for concern in China in the spring of 2013. Most H7N9 infections resulted in acute respiratory distress syndrome (ARDS), which is a severe form of acute lung injury (ALI) that contributes to morbidity and mortality. In this study, we induced viral ALI by infecting wild-type and CCL2-deficient mice with influenza H7N9 virus. The results sugges...
The emergence of severe cases of human influenza A (H7N9) viral infection in China in the spring of 2003 resulted in a global effort to rapidly develop an effective candidate vaccine. In this study, a cold-adapted (ca), live attenuated monovalent reassortant influenza H7N9 virus (Ah01/AA ca) was generated using reverse genetics that contained hemagglutinin (HA) and neuraminidase (NA) genes from...
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