abstract introduction: matrix metalloproteinase 2 is one of the inflammatory mediators that is involved in nociceptive processing and its production is regulated by many inflammatory factors such as nitric oxide. we studied the role of mmp-2 on the analgesic effects of nnos inhibitor. methods: considering that nitric oxide has many roles in pain processing, we studied the csf levels of mmp-2 af...

angioedema secondary to c1 inhibitor deficiency has been rarely reported to be associated with systemic lupus erythematosus. a genetic defect of c1 inhibitor produces hereditary angioedema, which is usually presented with cutaneous painless edema, but edema of the genital area, gastrointestinal and laryngeal tracts have also been reported. in lupus patients, angioedema may be the result of an a...

The idea of smart inhibitors is based on the principle that an inhibitor is used where needed. This will reduce the use of inhibitors and protect materials in hostile environments. On the other hand, direct addition of the inhibitor within the coating can be harmful, resulting in the loss of inhibitors ability, deterioration in the coating or both of them. An appropriate method for solving thes...

The performance of an Imidazoline based commercial corrosion inhibitor on CO2 corrosion of mild steel was investigated in a Cl- containing solution employing linear polarization resistance (LPR), potentiodynamic polarization and monitoring corrosion potential techniques. Experimental results showed that an increase of the commercial inhibitor concentration up to 500 ppm increases the RP value a...

development of inhibitor to factor viii is the most serious complication of hemophilia therapy. to determine the prevalence of inhibitors in iran hemophilia a patients exposed to blood products, 1280 hemophilia a patients (age range 9 months-84 years) were evaluated. all patients received several blood products such as fresh frozen plasma (ffp), cryoprecipitate, and factor viii. 635 of 1280 pat...

many investigations have proved relations between abo blood groups with some diseases and factor viii and von willebrand level in plasma. in this study we investigated a relation between abo blood groups and factor viii and ix inhibitors in 102 patients with haemophilia a and 48 patients with haemophilia b. the assay of inhibitor was done by bethesda method. there were no relation between abo b...

a case of a 40-year-old female, in whom a 6-meter long worm (taenia saginata) was found in stomach, is reported here. in this patient, t. saginata upward migration of the worm to the stomach, its rare phenomenon, worm mostly seen in the small intestine. this is mainly because of the high gastric acidity. in this patient, we believe proton pump inhibitor (ppi) use caused hypochlorhydria and coex...

conclusions vpa and cbz treatments caused a decrease in β-catenin and vegf levels in sw480 colon cancer cell lines. these results suggest that cbz can be considered a potential antitumor drug with potencies different from vpa. methods in the present experimental study, implemented during 2014 - 2015 in iran, after incubation of cells into 96-well plates with 5,500 cells/well, the tested drugs w...

background: hereditary angioedema (hae) is a rare autosomal dominant primary immunodeficiency with complement system defect characterized by recurrent episodes of angioedema involving the skin or mucosa of the upper respiratory and gastrointestinal tracts. objective: to characterize the clinical and laboratory data of hereditary angioedema in iran. methods: patients with probable diagnosis of a...