We determined mammalian cell invasion and virulence gene (inlA, inlB, and actA) sequences of Listeria monocytogenes strains belonging to a molecular subtype (RAPD 9) that often persists in Danish fish-processing plants. These strains invaded human placental trophoblasts less efficiently than other L. monocytogenes strains, including clinical strains, and they carry a premature stop codon in inl...

This work extends the Integrated Nested Laplace Approximation (INLA) method to latent models outside the scope of latent Gaussian models, where independent components of the latent field can have a near-Gaussian distribution. Two important class of models that can be addressed with our proposed method are non-Gaussian random effects models and dynamic models with non-Gaussian error term for the...

Variational methods for approximate Bayesian inference provide fast, flexible, deterministic alternatives to Monte Carlo methods. Unfortunately, unlike Monte Carlo methods, variational approximations cannot, in general, be made to be arbitrarily accurate. This paper develops grid-based variational approximations which endeavor to approximate marginal posterior densities in a spirit similar to t...

Age–period–cohort (APC) models have been widely used in the analysis of incidence and mortality data. Bayesian APC models, in which multivariate Gaussian priors are incorporated on age, period and cohort effects, can evade the identifiability problem. Inference with integrated nested Laplace approximations (INLA) has recently been a useful tool. An application of the Bayesian APC models with IN...

INTRODUCTION: This study aimed to determine the prevalence, and virulence factors of Listeria monocytogenes isolated from various samples by multiplex polymerase chain reaction (MPCR). METHODS: A total of 617 isolates were obtained and MPCR was employed for detection of the inlA, inlC, and inlJ genes. RESULTS: L. monocytogenes was detected in 46 (7.45%) of the 617 specimens. inlA, inlC, a...

A new method is proposed for modelling the yearly maxima of sub-daily precipitation, with aim producing spatial maps return level estimates. Yearly precipitation are modelled using a Bayesian hierarchical model latent Gaussian field, blended generalised extreme value (bGEV) distribution used as substitute more standard (GEV) distribution. Inference made less wasteful novel two-step procedure th...

In this paper we assess Bayesian estimation and prediction using integrated Laplace approximation (INLA) on a stochastic volatility model. This was performed through a Monte Carlo study with 1000 simulated time series. To evaluate the estimation method, two criteria were considered: the bias and square root of the mean square error (smse). The criteria used for prediction are the one step ahead...

Listeria monocytogenes internalin gene inlJ has been described previously for differentiation of virulent from avirulent strains. However, a recent report indicated that there exist some unusual lineage IIIB strains (e.g., serotype 7 strain R2-142) that possess no inlJ gene but have the capacity to cause mouse mortality via intraperitoneal inoculation. Therefore, a multiplex PCR incorporating i...