Background and Aim: Diabetes is a common disorder worldwide, and exhaustive efforts have been made to cure this disease. Gene therapy has considered as a potential curative method that has more stability in comparison with the other pharmaceutical methods. However, the application of gene therapy as a definitive treatment demands further investigation. This study aim is to prepare a suitable hi...

"Erratum to: “Relationships between insulin resistance and frailty with body composition testosterone in men undergoing androgen deprivation therapy for prostate cancer”" published on 01 Aug 2022 by Bioscientifica Ltd.

Insulin resistance as a hallmark of type 2 DM (T2DM) plays role in dementia by promoting pathological lesions or enhancing the vulnerability brain. Numerous studies related to insulin/insulin-like growth factor 1 (IGF-1) signaling are linked with various types dementia. Brain insulin is disturbances Aβ production and clearance, Tau hyperphosphorylation, microglial activation causing increased n...

Calcium channel blockers (CCB) overdose can result in cardiogenic shock and that high dose insulin euglycaemic therapy (HIET) is increasingly used to treat CCB poisoning. This case illustrates the ...

background: obesity has emerged as one of the most serious public health concerns in the 21st century. the consequences of this chronic disorder are serious. bariatric surgery has been shown to eliminate comorbid conditions associated with obesity. currently it is considered to be the only successful, long-term therapy for morbidly obese subjects.rnobjectives: the aim of this study was to evalu...