Fractional exhaled nitric oxide concentrations (FeNO) are elevated in asthmatic children and have been used inter alia to guide inhaled corticosteroid treatment in children [1]. Caffeine consumption might influence FeNO independently of asthma and more than one plausible mechanism has been identified. Studies in adults have reported changes in FeNO within 1 h of caffeine ingestion but the resul...

Ring-opening metathesis polymerization (ROMP) of rac-endo,exo-5,6-dicarbomethoxynorbornene (inter alia) yields a cis,syndio,alt-polymer, one in which the sequential units in the cis,syndiotactic polymer consist of alternating enantiomers. Cis selectivity arises through addition of the monomer to produce an all-cis-metallacyclobutane intermediate, while syndioselectivity and alternating enantiom...

Applications of operations research to mine planning date back to the 1960s. Since that time, optimization and simulation, in particular, have been applied to both surface and underground mine planning problems, including mine design, longand short-term production scheduling, equipment selection, and dispatching, inter alia. In this paper, we review several decades of such literature with a par...

New, effective antibiotics are only likely to become available in 15 - 20 years. To prevent deaths from untreatable Gram-negative infections in South Africa, the rights of any doctor, whether in general or in hospital practice, to indiscriminately prescribe whatever antibiotic they wish, and in whatever fashion, must be challenged. Furthermore, although prevention of the emergence and subsequen...

Let k be a nonzero, commutative ring with 1, and let R be a k-algebra with a countably-infinite ordered free k-basis B = {pn: n~>0}. We characterize and analyze those bases from which one can construct a k-algebra of 'formal B-series' of the form f = ~ c , p , , with cn Ek, showing inter alia that many classical polynomial bases fail to have this property. @ 1998 Elsevier Science B.V. All right...

Hypertension is common in the elderly. While it is possible to reduce blood pressure in this age group, the value of such treatment in terms of reduced mortality and morbidity is unknown. The effects of a prescribed regimen depends inter alia on compliance. Therefore, this variable must be taken into account in assessing drug treatment in the elderly hypertensive. In general, the elderly comply...

African countries, like other UNESCO member countries, commited themselves during the 2000 Dakar Global Forum to ensure quality education for all. It is a twofold challenge to equitably enhance access to and improve the quality of education. An exercise which requires inter alia, an inventive spirit, a review of existing policies and practices and an exchange of good ones particularly in the ar...

Time series cointegration tests, even in the presence of large sample sizes, often yield conflicting conclusions (“mixed signals”) as measured by, inter alia, a low correlation of empirical p-values [see Gregory et al., 2004, Journal of Applied Econometrics]. Using their methodology, we present evidence suggesting that the problem of mixed signals persists for popular panel cointegration tests....

The metatheory on the democratic process poses a conceptual framework for the empirical analysis of democratic processes in liberal democracies. A model of democratic processes is being developed which proceeds from certain metatheoretical presuppositions. It distinguishes, inter alia, between three subsystems of the political system and defines their relevant collective actors. Moreover, a con...

Metabolomics is the “omics” that studies the whole metabolome. It has a wide range of applications, inter alia chemotaxonomy, environmental influences, agriculture, etc. Here we review the application of metabolomics in natural product research. The importance of physicochemical properties to drug delivery are discussed in relation to turning metabolomic studies towards drug discovery. We belie...