نتایج جستجو برای: interpretive ranking process irp
تعداد نتایج: 1347198 فیلتر نتایج به سال:
PURPOSE To explore potential design for pharmacogenomics trials in sepsis, we investigate the interaction between pharmacogenomic biomarkers and response to drotrecogin alfa (activated) (DrotAA). This trial was designed to validate whether previously identified improved response polymorphisms (IRPs A and B) were associated with an improved response to DrotAA in severe sepsis. METHODS Patients...
Both policy debate and research have focused on the linkage between the availability and generosity of public disability benefits and the reduction in the work effort of older men. That linkage is the subject of this paper. First, quantitative research in the area is reviewed and the differences in the results are examined. Results differ owing to differences in (1) model specification, (2) the...
the purpose of this study was to examine the status of supervision on departments’ heads at ferdowsi university of mashhad (fum) and realize some applied themes to provide a fit model for supervising departments’ heads in fum. the method was case study under a research category aimed for applied one. using purposive sampling, interviews were conducted with top fum managers, head departments, an...
In its aconitase-inactive form, IRP-1 (iron regulatory protein-1)/cytosolic aconitase binds to the IRE (iron-responsive element) of several mRNAs to effect post-transcriptional regulation. We have shown previously that IRP-1 has ATPase activity and that binding of ATP suppresses the IRP-1/IRE interaction. In the present study, we characterize the binding activity further. Binding is observed wi...
TO THE EDITOR: Abdallah and Fass recently reported an interesting case of a patient with dysphagia who was initially diagnosed with Jackhammer esophagus (JE) and progressed to type 2 achalasia over the course of approximately 2 years. We read this report with great interest as our group has studied the natural course of JE and has also found progression of JE to achalasia, which we reported pre...
BACKGROUND Immune-related pancytopenia (IRP) is characterized by pancytopenia caused by autoantibody-mediated bone marrow destruction or suppression. The bone marrows of IRP patients have remarkably increased erythroblastic islands (EIs). METHODOLOGY AND PRINCIPAL FINDINGS We determined the immunoglobulin G (IgG) autoantibodies in some parts of EIs of IRP patients using immunofluorescence to ...
Genetic ablation of iron regulatory protein 2 (IRP-2), a protein responsible for post-transcriptional regulation of expression of several iron metabolism proteins, predisposes IRP-2 -/- mice to develop adult onset neurodegenerative disease. Ferric iron reproducibly accumulates within axonal tracts and neuronal cell bodies in discrete regions of the brain, and areas of iron accumulation colocali...
Run-time malware detection strategies are efficient and robust, which get more and more attention. In this paper, we use I/O Request Package (IRP) sequences for malware detection. N-gram will be used to analyze IRP sequences for feature extraction. Integrated use of Negative Selection Algorithm (NSA) and Positive Selection Algorithm (PSA), we get more than 96% true positive rate and 0% false po...
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