PURPOSE Positron emission tomography (PET) provides physiologic information that is not available from computed tomography (CT) or magnetic resonance studies. PET images may allow more accurate delineation of three-dimensional treatment planning target volumes of brachytherapy gynecologic (GYN) implants. This study evaluates the feasibility of using PET as the sole source of target, normal stru...

The quality of life (QoL) patients with cervical cancer is paramount concern in addition to their survival outcomes. rationale this study was assess the QoL locally advanced treated chemoradiation and estimate its difference when two different brachytherapy (BT) techniques: Intracavitary (ICRT) or Interstitial (ISBT). Forty-five, previously untreated, carcinoma cervix FIGO stage IIB IVA who wer...

BACKGROUND Traditionally, low dose rate (LDR) brachytherapy has been used as a standard modality in the treatment of patients with carcinoma of the uterine cervix. The purpose of this work was to evaluate the effects of high dose rate (HDR) brachytherapy on patients with adenocarcinoma of the uterine cervix and to compare them with the effects of LDR brachytherapy. METHODS From January 1971 t...

BACKGROUND Interstitial brachytherapy (ISBT) is an optional treatment for locally advanced gynecological tumours for which conventional intracavitary brachytherapy (ICBT) would result in suboptimal dose coverage. However, ISBT with Martinez Universal Perineal Interstitial Template (MUPIT), in which ~10-20 needles are usually applied, is more time-consuming and labor-intensive than ICBT alone, m...

PURPOSE Brachytherapy plays a major role in the treatment of patients with carcinoma of the cervix. However, routine intracavitary brachytherapy may not be feasible or adequate to treat locally advanced disease. The purpose of this retrospective study (spanning a 20-year period) was to determine the outcome of interstitial low-dose-rate brachytherapy in the treatment of bulky or locally advance...

PURPOSE To retrospectively assess the incidence of sub-serosal and uterine perforation of intra-uterine tandem in intracavitary high-dose-rate (HDR) brachytherapy for cervical cancer, and to evaluate its dosimetric implications on computed tomography (CT)-based treatment planning. MATERIAL AND METHODS Computed tomography images and brachytherapy plans of cervical cancer patients treated from ...

Aim Since anatomical and geometric variations occur with every fraction, planning, and dose optimization is necessary for every fraction of high-dose rate intracavitary brachytherapy of carcinoma cervix. In this study, we have tried to quantify the differences in doses to organs at risk (OAR) for each fraction of brachytherapy. Methods and Materials One hundred and seventy computed tomography...

Background: Concurrent chemoradiotherapy (CCRT) plus intracavitary brachytherapy (ICBT) is standard of care for locally advanced cervical cancer (LACC). However, because differences in tissue response and anatomy, sometimes fails to deliver adequate doses may result higher recurrence rates. Thus, there have been studies discussing the role adjuvant hysterectomy (AH). National Comprehensive Canc...

Brachytherapy plays a significant role in the management of cervical cancer, but the clinical significance of brachytherapy in the management of vaginal cancer remains to be defined. Thus, a single institutional experience in the treatment of primary invasive vaginal carcinoma was reviewed to define the role of brachytherapy. We retrospectively reviewed the charts of 36 patients with primary va...