Intracranial hydatid disease is a parasitic infection that affects children in endemic areas such as the Mediterranean, South America, and Australia. In non-endemic areas, it is rare and may pose a diagnostic dilemma. We review a boy who presented with a right cerebral cyst. All investigations were negative, and hydatid cyst was encountered upon intra-operative exploration. We review the availa...

To investigate whether the observed association of leukoaraiosis with intracerebral hemorrhage is direct or mediated by risk factors, we compared 116 patients with intracerebral hemorrhage confirmed by computed tomography and 155 controls without intracerebral hemorrhage, evaluating the prevalence of leukoaraiosis and vascular risk factors. Leukoaraiosis was observed in 21 (18%) of the 116 pati...

Neurogenesis occurs in discrete regions of normal brains of adult mammals including humans, and is induced in response to brain injury and neurodegenerative disease. Whether intracerebral hemorrhage can also induce neurogenesis in human brain is unknown. Specimens were obtained from patients with primary intracerebral hemorrhage undergoing surgical evacuation of an intracerebral hematoma, and e...

Cerebral myeloma in a 49-year-old white man took the form of diffuse arachnoid infiltration, intracerebral perivascular cuffing, and frank intracerebral invasion.

OBJECTIVE Hydrogen inhalation was neuroprotective in several brain injury models. Its mechanisms are believed to be related to antioxidative stress. We investigated the potential neurovascular protective effect of hydrogen inhalation especially effect on mast cell activation in a mouse model of intracerebral hemorrhage. DESIGN Controlled in vivo laboratory study. SETTING Animal research lab...

BACKGROUND Delayed intracerebral hemorrhage after ventriculoperitoneal (VP) shunt insertion is rare and has not been well investigated previously. Its characteristics is still unknown. OBJECTIVE We reported 12 patients with delayed intracerebral hemorrhage after VP shunt to investigate the potential risk factors and the outcome. RESULTS 12 patients (1.59%) of all the 754 hydrocephalus had d...

Type I collagen (transcribed by COL1A1 and COL1A2 genes) is important for maintaining vessel wall elasticity and is a critical part of the extracellular matrix. We conducted a case-control study to investigate the role of the COL1A2 rs42524 polymorphism in the development of hypertensive intracerebral hemorrhage. Between January 2012 and December 2014, a total of 227 patients with hypertensive ...

In intracerebral haemorrhage, the most frequent underlying vasculopathies are cerebral amyloid angiopathy and hypertensive vasculopathy. Although both are associated with cognitive impairment, no study has focused on pre-existing dementia in patients with intracerebral haemorrhage. Therefore, we aimed to determine prevalence and mechanisms of pre-existing dementia in a large cohort of patients ...

Since one of us (J.N.C.) in 1953 recorded the results of electrophoresis on paper of the proteins of the cerebrospinal fluid and cerebral cyst fluids a number of other supporting media have been employed for this purpose. Some, such as starch, are valuable because of a higher resolving power and a greater ability to separate many of the protein components. The use of the polyacrylamide disc ele...

Cryptococcal infection of the brain as encountered in a tropical country is reviewed. The meningitic form is not uncommon and there has been, in the last decade, an apparent, if not real, rise in incidence in Malaysia as in Singapore. Only exceptionally was there overt evidence of immunological deficiency. Hydrocephalus was present in about three-quarters of the patients with meningitis and shu...