BACKGROUND AND OBJECTIVES Oral submucous fibrosis (OSMF) is a potentially malignant disorder of oral mucosa affecting mainly population in South and Southeast Asia. The aim of this study is to compare the effectiveness of oral colchicine with intralesional injection of hyaluronidase or injection triamcinolone acetonide in patients with Grade II OSMF. MATERIALS AND METHODS The study included t...

BACKGROUND Warts are common and induce physical and emotional discomfort. Numerous therapies exist, yet none is optimal. Despite theoretical advantages, immunotherapeutic modalities are often neglected as first-line wart therapies. OBJECTIVE To compare treatment with intralesional skin test antigen injection of 1 wart vs cryotherapy of all warts. DESIGN Pilot study. SETTING University der...

BACKGROUND Polyacrylamide gels, containing a hydrogel composed of polyacrylamide and water, are used for soft tissue augmentation and contour correction. There are no reports of significant complications after injection of this material into the face. OBJECTIVE We report an inflammatory reaction after injection of polyacrylamide gels for zygomatic facial augmentation. METHODS A retrospectiv...

Stricture frequently occurs after endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma with near- or whole-circumferential mucosal defects, and post-ESD stricture is difficult to treat and usually requires multiple sessions of endoscopic balloon dilatation. Intralesional steroid injection has previously been used to prevent stricture; however, there have been few experien...

Background. Ingrown nails are a type of nonspecific inflammation nail folds. Intralesional injection is rarely reported nonsurgical therapy for ingrown nails. Objective. To observe the efficacy treating with intralesional injection, and to evaluate at which stage applicable this therapy. Methods. were randomly divided into treatment (n = 87) control 37) groups. The group received local injectio...

Objective. To investigate the clinical efficacy and safety of intralesional injection of 2% zinc sulfate solution in the treatment of common warts. Patients and Methods. One hundred and twenty patients (78 females and 42 males) aged 5-55 years with 225 common warts participated in this prospective monocentric randomized study. All lesions were treated with intralesional injection of 2% zinc sul...

Background: An easy and effective topical treatment is not yet available for cutaneous leishmaniasis. Objectives: To compare the effect of topical trichloroacetic acid (TCA) and intralesional glucantime injection in the treatment of acute wet cutaneous leishmaniasis. Patients and Methods: Eighty patients with clinical diagnosis of wet cutaneous leishmaniasis in the age range of 5 to 75 years we...

Background: A keloid is dysregulated firoproliferative scar tissue in response to skin injuries, which extends beyond the wound margin. Since it has a poor response to treatment, variable therapies are used. Current therapies of keloid include intralesional corticosteroid injection, cryotherapy and various laser therapies, silicone gel sheets (pressure therapy), interferon-α-2b, 5floruracilorbl...