Pseudomembranous necrotising bronchial aspergillosis is a variety of invasive aspergillosis found in immunosuppressed patients. A case is presented of a 66 year old woman whose only underlying disease was chronic airways limitation. The pathological findings and clinical implications are discussed.

Two patients with invasive aspergillosis had unusual endobronchial appearances at fibreoptic bronchoscopy. Diagnosis was achieved by endobronchial biopsy.

Combination antifungal therapy is increasingly used in the treatment of invasive aspergillosis. Whether the interaction between amphotericin B and triazoles is antagonistic against invasive aspergillosis is a controversial issue that is not likely to be resolved through a randomized clinical trial. Here, we found both in vitro and in vivo antagonism between liposomal amphotericin B and ravucona...

Purpose: Patients with acute respiratory distress syndrome (ARDS) due to viral infection admitted at ICU are risk for secondary complications like invasive pulmonary aspergillosis. Our study evaluates severe ARDS COVID-19 associated aspergillosis a single center in Madrid, Spain. Materials and Methods: A retrospective chart review of patients two the five ICUs that were available Gregorio Maran...

Prolonged neutropenia is generally thought to be the major factor for invasive pulmonary aspergillosis (IPA). In the present study, we characterize the frequency, severity, and duration of neutropenia that immediately precedes IPA. Prolonged neutropenia was identified in only one third of all IPA cases and occurred exclusively in hematologic patients.

introduction: invasive aspergillosis is a major cause of morbidity and mortality in hematologic malignant patients which have received intensive cytotoxic therapy or undergone blood and marrow transplantation (bmt). early clinical and radiological diagnosis of ia is almost impossible and so mortality is very high. the main purpose of our study was to assay the diagnostic value of serum galactom...

OBJECTIVE We retrospectively investigated the clinical features of pulmonary aspergillosis associated with interstitial pneumonia. METHODS We reviewed the medical records of all patients treated for interstitial pneumonia with or without pulmonary aspergillosis at our institution between April 2006 and August 2012 and evaluated the clinical features as well as risk and prognostic factors for ...

A prospective study was conducted in 38 patients with nodular lesions on plain chest radiographs and the clinical suspicion of invasive pulmonary aspergillosis (IPA) to assess the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT). For early diagnosis of IPA (clinical signs and symptoms <10 days), CT scans with demonstration of the halo sign had a high sensitiv...

INTRODUCTION Invasive pulmonary aspergillosis (IPA) is an important cause of morbidity and mortality in a wide range of patients. Early recognition and diagnosis have become a major focus in improving the management and outcomes of this life-threatening disease. BACKGROUND IPA typically occurs during a period of severe and prolonged neutropenia. However, solid organ transplant recipients, pat...