introduction: the wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.methods: this case series study included 62 patients with wilson disease who admitted to children&apo...

HTLV-1 is the causative agent for a neurologic disease named HTLV-I- associated myelopathy/tropical spastic paraparesis (HAM/TSP). Paraparesis of the lower limbs which appears gradually is the most common clinical feature of this disease. The indirect involvement of the nervous system by lymphocytes is more probable than the direct attack of the virus to the neurons. The proviral load (PVL) is ...

Background HIV causes diseases of respiratory system in various ways. The lung involvement may be of infective etiology or non-infective like Kaposi’s sarcoma or pulmonary hypertension. In India with the load of pulmonary tuberculosis, immuno-compromised patients are exposed to the risk of tuberculosis. This study endeavors to identify the patients who get lung involvement secondary to HIV infe...

Contractile tissues demonstrate a pronounced capacity to remodel their composition in response to mechanical challenges. Descriptive evidence suggests the upstream involvement of the phosphotransfer enzyme FAK (focal adhesion kinase) in the molecular control of load-dependent muscle plasticity. Thereby FAK evolves as a myocellular transducer of mechanical signals towards downstream transcript e...

Patients with a tuberculoma typically present with pulmonary involvement of tuberculosis and have risk factors for tuberculosis (TB). The risk factors for tuberculosis include bacillary load, proximity to infectious case, immunosuppressive conditions, malnutrition, young age, diabetes mellitus, working in healthcare, recent incarceration, alcohol use, and tobacco use. Although rare, it is possi...

background the immune system plays important roles in determining the outcomes of hepatitis c virus (hcv) infection. interleukin-23 and -27 (il-23 and il-27) are two novel il-12 cytokine family members known to enhance the t-lymphocyte response, but their precise involvement in hcv infection is not well known. objectives we investigated the serum il-27 and il-23 levels in patients with hcv infe...