A method for measuring muscle fiber capacitance using small test pulses applied with the three-microelectrode voltage clamp is presented. Using this method, three membrane potential-dependent changes in capacitance were observed: (a) Capacitance of polarized fibers increased by 5--15% with depolarization from V less then -100 mV to voltages slightly below the contraction threshold. (b) Capacita...

The high eccentricities of the known extrasolar planets remain largely unexplained. We explore the possibility that eccentricities are excited in the outer parts of an extended planetary disk by encounters with stars passing at a few hundreds of AU. After the encounter, eccentricity disturbances propagate inward due to secular interactions in the disks, eventually exciting the innermost planets...

The roles of cyclic nucleotide-gated (CNG) channels in sensory transduction have long been recognized. More recent studies found that CNG channels are distributed in multiple brain regions involved in memory and learning, including the cortex, hippocampus and cerebellum. These findings suggest that their functions are not limited to sensory perception, but also to neuronal plasticity phenomena,...

The roles of cyclic nucleotide-gated (CNG) channels in sensory transduction have long been recognized. More recent studies found that CNG channels are distributed in multiple brain regions involved in memory and learning, including the cortex, hippocampus and cerebellum. These findings suggest that their functions are not limited to sensory perception, but also to neuronal plasticity phenomena,...

For shallow caps under an axisymmetric external pressure distribution which is inward (with a representative magnitude pO) in a neighborhood of the pole and outward away from the pole, it has been shown previously that a finite axisymmetric dimple state of deformation is possible if p0 is at least of the order of the classical buckling pressure for a complete spherical shell, Pi, and that, asym...

Early afterdepolizations (EADs) induced by suppression of cardiac delayed rectifier IKr and/or IKs channels cause fatal ventricular tachyarrhythmias. In guinea-pig ventricular myocytes, partial block of one of the channels with complete block of the other reproducibly induced EADs. Complete block of both IKr and IKs channels depolarized the take-off potential and reduced the amplitude of EADs, ...

Korean red ginseng (KRG) has been used worldwide as a traditional medicine for the treatment of various reproductive diseases. Gonadotropin releasing hormone (GnRH) neurons are the fundamental regulators of pulsatile release of gonadotropin required for fertility. In this study, an extract of KRG (KRGE) was applied to GnRH neurons to identify the receptors activated by KRGE. The brain slice pat...

Abstract: activity gas diffusion process has been investigated in this research. Effects of coating temperature and aluminumconcentration in powder mixture on formation mechanism were studied using optical and scanning electronmicroscopes, EDS and X-ray diffraction (XRD) techniques. For this purpose two different packs containing 1 and 2wt% aluminum powder, were used for coating the samples at ...