background: the aim of the study was to evaluate the third trimester urinary iodine excretion and to assess its relation with newborns thyroid function. materials and methods: a total  of  208 healthy third trimester pregnant women without previous history of thyroid disease were included in the study. urinary iodine levels of mothers were measured and neonatal tsh levels were screened on the 3...

background & objectives: iodine deficiency disorder (idd) is the most common endocrine disorder in the world. it is estimated that about 1.5 billion people are in iodine deficiency state. many studies have shown the high prevalence of endemic goiter and iodine deficiency in iran.  for control of this health problem salt iodinization is the best  accepted strategy in the world. the main objectiv...

Background. Iodine deficiency in pregnancy is a worldwide problem. This study aimed to assess prevalence and predictors of subclinical iodine deficiency among pregnant women in Haramaya district, eastern Ethiopia. Methods. A cross-sectional, community-based study was conducted on 435 pregnant women existing in ten randomly selected rural kebeles (kebele is the smallest administrative unit in Et...

Endemic cretinism includes two syndromes: a more common neurological disorder with brain damage, deaf mutism, squint and spastic paresis of the legs and a less common syndrome of severe hypothyroidism, growth retardation and less severe mental defect. Both conditions are due to dietary iodine deficiency and can be prevented by correction of iodine deficiency before pregnancy. Endemic cretinism ...

Severe iodine deficiency causes hypothyroidism that results in impaired somatic growth and motor development in children. Mild and moderate iodine deficiencies cause multifocal autonomous growth of thyroid, which results in thyrotoxicosis. On the other hand, iodine excess is associated with the development of hypothyroidism and thyroid autoimmunity. In areas of iodine deficiency, a sudden incre...

OBJECTIVE The iodine intake level in a population is determined in cross-sectional studies. A fraction of samples with iodine content below a certain level, e.g. 25 microg/l, may suggest iodine deficiency in part of the population. However, urinary iodine varies considerably from day to day and the fraction of low samples caused by dispersion remains unsettled. DESIGN A longitudinal study of ...

OBJECTIVE To review methods for evaluating iodine deficiency in pregnant women and young infants and to discuss factors to be considered in the interpretation of their results. DESIGN Review of the literature regarding the various methods available for assessing iodine status. SETTING Population surveys and research studies. SUBJECTS Pregnant women and young infants. RESULTS Several fac...

Selenium deficiency causes further impairment of thyroid hormone metabolism in iodine-deficient rats and therefore could have a role in the aetiology of both myxoedematous and neurological cretinism in humans. Thyroidal type I iodothyronine deiodinase (ID-I), cytosolic glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase activities were increased in iodine-deficient adul...