BACKGROUND No direct comparisons exist of the renal tolerability of the low-osmolality contrast medium iopamidol with that of the iso-osmolality contrast medium iodixanol in high-risk patients. METHODS AND RESULTS The present study is a multicenter, randomized, double-blind comparison of iopamidol and iodixanol in patients with chronic kidney disease (estimated glomerular filtration rate, 20 ...

BACKGROUND No clinical trial has yet focused on contrast-mediated nephrotoxicity in patients with chronic renal failure exclusively undergoing percutaneous coronary intervention (PCI). Therefore, the aim of this study was to compare the effect of contemporary contrast media on nephrotoxicity in this high-risk patient population. METHODS AND RESULTS This prospective, randomized, double-blind, ...

OBJECTIVES We sought to compare the nephrotoxicity of isosmolar contrast medium (IOCM) iodixanol with low-osmolar contrast media (LOCM) and to identify predictors of contrast-induced nephropathy (CIN). BACKGROUND Contrast-induced nephropathy is a serious complication of diagnostic and interventional procedures. METHODS Pooled individual patient data (n = 2,727) from 16 double-blind, randomi...

BACKGROUND There is no consensus and a limited evidence base for choice of contrast agents (CA) in angiography. This study evaluated the impact of iohexol and iodixanol CA on fibrinolytic factors (tissue plasminogen activator [t-PA] and plasminogen activator inhibitor-1 [PAI-1]), as well as platelet-monocyte conjugates in cardiac patients undergoing elective angiography in a double-blind, rando...

Iodixanol (IDX) is a water soluble opacifier widely used in radiographical examinations of blood vessels and neural tissue, and it has been suggested as a potential contrast media in acrylic bone cement. The effect of the iodixanol particle size on the polymerisation process of the bone cement, the molecular weight, and the quasi-static mechanical properties have been investigated in this artic...

Iodixanol provides an easy and affordable solution to a problem that has limited resolution and brightness when imaging living samples.

determination of normal gastric emptying time and small intestinal transit time are useful in detecting gastrointestinal motility disorders and partial obstructions of the pylorus or small intestine. this study was conducted to evaluate iodixanol as a contrast agent in the gastrointestinal tract in new zealand white rabbit. twelve clinically healthy adult rabbits were prepared and kept for two ...

Determination of normal gastric emptying time and small intestinal transit time are useful in detecting gastrointestinal motility disorders and partial obstructions of the pylorus or small intestine. This study was conducted to evaluate iodixanol as a contrast agent in the gastrointestinal tract in New Zealand White rabbit. Twelve clinically healthy adult rabbits were prepared and kept for two ...