• PK216LH, which is a cation-exchange resin, could remove NH 4 + in an aqueous solution. The simultaneous use of Mg–Al LDO and PK216LH not sufficiently lactate . individual two stages efficient proliferation pluripotent stem cells mass cell culture hindered by the release metabolites such as ammonia. In this work, porous strong-acid cation exchange resin (PK216LH) layered doubled oxide (LDO) we...

An integrated all flow-through technology platform for the purification of therapeutic monoclonal antibodies (mAb), consisting of activated carbon and flow-through cation and anion exchange chromatography steps, can replace a conventional chromatography platform. This new platform was observed to have excellent impurity clearance at high mAb loadings with overall mAb yield exceeding 80%. Robust...

Ion exchange resins have versatile properties as drug delivery vehicles and have been extensively studied in the development of novel drug delivery systems1. Cation exchange resins containing strong sulfonic acid group form a strong bond with cationic drugs and elution of drug from resinates is slower2. Formulations based on ion exchange resins are successfully marketed viz Pennkinetic system b...

salicylic acid-formaldehyde-m-cresol (sfm) terpolymer had been synthesized in dmf media by conventional method. the resulting resin had been characterized by ftir spectra, elemental and thermogravimetric analyses. the morphology of sfm resin had been studied by sem and optical photograph. various parameters like rate of equilibration, effect of ph on ion exchange capacity and effect of concentr...

The influence of simple salts on the ion exchange and protonation equilibria of an amphoteric ion-exchange resin, which has strong base and weak acid moieties in a single functional group fixed onto the styrene-DVB matrix, has been investigated. Concentrations of ionic species in the amphoteric ion-exchange resin in equilibrium with various sodium salt solutions were estimated by (23)Na NMR spe...

An attempt was made to sustain the release of metformin HCl as well as to mask the bitter taste by complexation technique using strong cation-exchange resins, indion 244 and indion 264. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug:resin and temperature. The resinate was evaluated for micromeritic properties, tast...

The Jaff#{233} reaction is commonly used to determine the concentration of creatinine in urine and serum by measuring the color produced when picric acid and sodium hydroxide solutions are combined with urine or protein-free filtrate from serum. As is well known, substances other than creatinine react to give positive error, the relative amount of interference usually being much greater in seru...

a polyamine-formaldehyde resin (Amberlite IR-4) as an anion exchange resin on the gastric secretions of rats. The acid neutralizing characteristics of the resin suggested its trial in the treatment of peptic ulcer but the large volume required to remove clinical amounts of acid from solution rendered its use impractical, even though feeding experiments showed the substance to be innocuous. Howe...