Although bacteria use different iron compounds in vitGro, the possibility that microbes distinguish between these iron sources during infection has hitherto not been examined. We applied stable isotope labeling to detect source-specific iron by mass spectrometry and show that Staphylococcus aureus preferentially imports heme iron over transferrin iron. By combining this approach with computatio...

Entamoeba histolytica is an ameboid parasite that causes colonic dysentery and liver abscesses in humans. The parasite encounters dramatic changes in iron concentration during its invasion of the host, with relatively low levels in the intestinal lumen and then relatively high levels in the blood and liver. The liver notably contains sources of iron; therefore, the parasite's ability to use the...

Pleurotus ostreatus is able to bioaccumulate several metals in its cell structures; however, there are no reports on its capacity to bioaccumulate iron. The objective of this study was to evaluate cultivation variables to increase iron bioaccumulation in P. ostreatus mycelium. A full factorial design and a central composite design were utilized to evaluate the effect of the following variables:...

The level of available iron in the mammalian host is extremely low, and pathogenic microbes must compete with host proteins such as transferrin for iron. Iron regulation of gene expression, including genes encoding iron uptake functions and virulence factors, is critical for the pathogenesis of the fungus Cryptococcus neoformans. In this study, we characterized the roles of the CFT1 and CFT2 ge...

Iron deficiency anemia(IDA) is one of the most common nutritional problems in the world.children under 5 years old are considerd as the high risk group consisting a high proportion of IDA patients.in this group,due to the specific conditions,the complication of anemia may lead to serious consequences.this study was designed to determine the prevalence of IDA in 1-5 years old children.A total of...

Iron and vitamin A deficiencies in childhood are public health problems in the developing world. Introduction of cereal-based complementary foods, that are often poor sources of both vitamin A and bioavailable iron, increases the risk of deficiency in young children. Alternative foods with higher levels of vitamin A and bioavailable iron could help alleviate these micronutrient deficiencies. Th...

BACKGROUND The cowpea (Vigna unguiculata L. Wap.) is an excellent source of iron and zinc. However, iron from plant sources is poorly absorbed compared with iron from animal sources. OBJECTIVES The objective of this study was to evaluate iron and zinc bioaccessibility in cowpea cultivars after processing. METHODS Zinc and iron bioaccessibilities in cowpea samples were determined based on an...

Iron is an essential element for almost all living species. Its environmental impacts on physiology and ecology of aquatic organisms are always the focus of limnology and oceanography. To gain insight into iron biogeochemistry and its environmental impacts in freshwater lakes, we collected and reviewed numerous studies on iron in combination with our own work. Our review reports iron sources, i...

We selected a sample of eight bright unobscured (at least at the iron line energy) Seyfert Galaxies observed simultaneously by XMM-Newton and BeppoSAX, taking advantage of the complementary characteristics of the two missions. The main results of our analysis can be summarized as follows: narrow neutral iron lines are confirmed to be an ubiquitous component in Seyfert spectra; none of the analy...