Escherichia coli contains at least two iron storage proteins, a ferritin (FtnA) and a bacterioferritin (Bfr). To investigate their specific functions, the corresponding genes (ftnA and bfr) were inactivated by replacing the chromosomal ftnA and bfr genes with disrupted derivatives containing antibiotic resistance cassettes in place of internal segments of the corresponding coding regions. Singl...

regarding the importance of the customer in today'scompetitive world, and considering the previous researches whichindicated the cost of attracting new customers is far more than the costof maintaining customer loyalty, studying the methods of obtainingand maintaining customer loyalty in various businesses has received ahigh priority. the purpose of this study is to determine thecomponents...

Iron is a vital nutrient to promote the availability of tissue oxygen, cell growth and control differentiation, energy metabolism. Preventing Deficiency Anemia (IDA) necessary because iron central nervous system development especially in first years life. Iron-rich complementary foods are recommended infants around 6 months age store depleted. Better understanding absorption process factors aff...

BACKGROUND Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years have witnessed a renewed interest in this strategy because of availability of...

Background: Iron deficiency anemia is one of the important problems during pregnancy. Iron deficiency has several adverse effects on pregnant women and their newborns. Objective: To determine the status of iron store in newborns born to mothers with iron deficiency anemia. Methods: In a cross-sectional study, 90 mothers were categorized into three groups according to their pre-delivery hemoglob...

Iron is an essential element needed by all organisms for growth and development. Because iron becomes toxic at higher concentrations iron is under homeostatic control. Plants face also the problem that iron in the soil is tightly bound to oxygen and difficult to access. Plants have therefore developed special mechanisms for iron uptake and regulation. During the last years key components of pla...

Mitochondrial ferritin (MtF) is structurally and functionally similar to the cytosolic ferritins, molecules designed to store and detoxify cellular iron. MtF expression in human and mouse is restricted to the testis and few tissues, and it is abundant in the erythroblasts of patients with sideroblastic anemia, where it is thought to protect the mitochondria from the damage caused by iron loadin...

Mitochondrial ferritin (MtF) is structurally and functionally similar to the cytosolic ferritins, molecules designed to store and detoxify cellular iron. MtF expression in human and mouse is restricted to the testis and few tissues, and it is abundant in the erythroblasts of patients with sideroblastic anemia, where it is thought to protect the mitochondria from the damage caused by iron loadin...

ELUCIDATION OF THE FUNCTIONAL ROLE OF PCBP-THE CYTOSOLIC IRONCHAPERONE PROTEIN FAMILY, IN CELLULAR IRON HOMEOSTASISbyPOORNA SUBRAMANIANAugust 2013Advisors: Dr. Timothy Stemmler and Dr. Brian EdwardsMajor: Biochemistry and Molecular BiologyDegree: Doctor of PhilosophyBiological Role of Ferritin Iron is essential for life and often utilized as a cofactor in man...